SCHEMBL6037459

SCHEMBL6037459

C=C(CCCCC)N1CCNCC1

nearest known ligand 0.46

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
GNAI3 P08754 10/20 0.46
GNAI1 P63096 10/20 0.46
GNAO1 P09471 9/20 0.46
L3MBTL1 Q9Y468 2/20 0.40
FAAH O00519 1/20 0.40
NAAA Q02083 1/20 0.40
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
HRH2 P25021 1/20 0.39
HRH1 P35367 1/20 0.39
CNR2 P34972 1/20 0.36
SIGMAR1 Q99720 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5141324 0.82 L3MBTL1 (0.59) GNAI3GNAI1L3MBTL1FAAHNAAA
SCHEMBL10687056 0.80 L3MBTL1 (0.60) GNAI3GNAI1L3MBTL1MEN1KMT2A
SCHEMBL19051850 0.78 L3MBTL1 (0.58) GNAI3GNAI1GNAO1L3MBTL1FAAH
SCHEMBL18914399 0.77 CHRNB2 (0.40) SIGMAR1
SCHEMBL1073791 0.77 L3MBTL1 (0.69) GNAI3GNAI1GNAO1L3MBTL1FAAH
SCHEMBL23533349 0.76 GNAI3 (0.69) GNAI3GNAI1GNAO1L3MBTL1FAAH
SCHEMBL6488462 0.76 GNAI3 (0.69) GNAI3GNAI1GNAO1L3MBTL1FAAH
SCHEMBL3601270 0.76 GNAI3 (0.69) GNAI3GNAI1GNAO1L3MBTL1FAAH
SCHEMBL8973060 0.76 GNAI3 (0.69) GNAI3GNAI1GNAO1L3MBTL1FAAH
SCHEMBL6536788 0.76 GNAI3 (0.69) GNAI3GNAI1GNAO1L3MBTL1FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006000913-A1 METHOD FOR STERILE FILTRATION OF VISCOUS PHARMACEUTICAL COMPOSITIONS PFIZER PRODUCTS INC. (US) 2006-01-05 WO disclosed