Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPA3 | P15088 | 1/20 | 0.40 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | CCKBR | P32239 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5053089 | 0.87 | GRM3 (0.50) | FOLH1 | |
| SCHEMBL7607893 | 0.81 | GRM3 (0.48) | FOLH1 | |
| SCHEMBL8427851 | 0.77 | FOLH1 (0.47) | CPA3FOLH1CCKBR | |
| SCHEMBL7605215 | 0.75 | FOLH1 (0.48) | CPA3FOLH1 | |
| SCHEMBL7605358 | 0.75 | GGH (0.52) | CCKBR | |
| SCHEMBL5057964 | 0.75 | CCKBR (0.39) | FOLH1HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL6037845 | 0.74 | NPSR1 (0.49) | CPA3FOLH1 | |
| SCHEMBL6037833 | 0.74 | NPSR1 (0.49) | CPA3FOLH1 | |
| SCHEMBL6037791 | 0.73 | FOLH1 (0.46) | CPA3FOLH1 | |
| SCHEMBL5057813 | 0.73 | FOLH1 (0.48) | CPA3FOLH1CCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006093991-A1 | COMPOUNDS WHICH BIND PSMA AND USES THEREOF | THE CLEVELAND CLINIC FOUNDATION (US) | 2006-09-08 | — | — | WO | disclosed |