Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5053089 | 0.89 | GRM3 (0.50) | GRM3FOLH1 | |
| SCHEMBL8060092 | 0.81 | MMP3 (0.43) | — | |
| SCHEMBL6037834 | 0.81 | CPA3 (0.40) | FOLH1 | |
| SCHEMBL5057813 | 0.79 | FOLH1 (0.48) | GRM3FOLH1 | |
| SCHEMBL5060436 | 0.78 | CYP1A2 (0.52) | GRM3FOLH1 | |
| SCHEMBL5053123 | 0.78 | FOLH1 (0.61) | GRM3FOLH1 | |
| SCHEMBL29417817 | 0.76 | MTNR1A (0.60) | — | |
| SCHEMBL606161 | 0.76 | MTNR1A (0.60) | — | |
| SCHEMBL5053304 | 0.76 | GRM3 (0.51) | GRM3FOLH1 | |
| SCHEMBL8427851 | 0.76 | FOLH1 (0.47) | GRM3FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2002514184-A | — | — | 2002-05-14 | — | — | JP | claimed |
| EP-1005348-A1 | NAALADASE COMPOSITIONS AND METHODS FOR TREATING GLUTAMATE ABNORMALITY AND EFFECTING NEURONAL ACTIVITY IN ANIMALS | GUILFORD PHARMACEUTICALS INC. (US) | 2000-06-07 | — | — | EP | claimed |
| WO-1998013046-A1 | NAALADASE COMPOSITIONS AND METHODS FOR TREATING GLUTAMATE ABNORMALITY AND EFFECTING NEURONAL ACTIVITY IN ANIMALS | GUILFORD PHARMACEUTICALS INC. (US) | 1998-04-02 | — | — | WO | claimed |
| US-6413948-B1 | CENTRAL NERVOUS SYSTEM DISORDERS | GUILFORD PHARMACEUTICALS INC. | 2002-07-02 | — | — | US | disclosed |