Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TTR | P02766 | 1/20 | 0.32 |
| ▸ | CASP6 | P55212 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29148497 | 0.78 | ALDH1A1 (0.32) | ALDH1A1HIF1AMAPTCA1CA14 | |
| SCHEMBL18478 | 0.78 | TSHR (0.42) | TDP1ATMALDH1A1KMT2AMEN1 | |
| SCHEMBL9789544 | 0.76 | CYP1A2 (0.36) | TDP1ALDH1A1KMT2AMEN1BCHE | |
| SCHEMBL6676890 | 0.76 | GPR35 (0.52) | TDP1ALDH1A1HIF1AKMT2AMEN1 | |
| SCHEMBL23581895 | 0.76 | ALDH1A1 (0.37) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL6514635 | 0.76 | AR (0.38) | TDP1ATMALDH1A1HIF1AKMT2A | |
| SCHEMBL18311461 | 0.73 | TDP1 (0.56) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL301081 | 0.72 | TSHR (0.41) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL301080 | 0.72 | TDP1 (0.34) | TDP1ATMALDH1A1HIF1AVCAM1 | |
| SCHEMBL1355833 | 0.72 | ALDH1A1 (0.42) | TDP1ALDH1A1KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060165701-A1 | Agents for the diagnosis and treatment of tumors that expose alerted proteins on the cell surface | BRACCO IMAGING S.P.A. (IT) | 2006-07-27 | — | — | US | disclosed |
| CN-1711106-A | Agents for the diagnosis and treatment of tumours that expose altered proteins on the cell surface | BRACCO IMAGING SPA (IT) | 2005-12-21 | — | — | CN | disclosed |
| EP-1587536-A1 | AGENTS FOR THE DIAGNOSIS AND TREATMENT OF TUMOURS THAT EXPOSE ALTERED PROTEINS ON THE CELL SURFACE | BRACCO IMAGING S.p.A. (IT) | 2005-10-26 | — | — | EP | disclosed |
| WO-2004043487-A1 | AGENTS FOR THE DIAGNOSIS AND TREATMENT OF TUMOURS THAT EXPOSE ALTERED PROTEINS ON THE CELL SURFACE | BRACCO IMAGING S.P.A. (IT) | 2004-05-27 | — | — | WO | disclosed |
| EP-0538392-A1 | 3-PHENYL-5,6-DIHYDROBENZ C]ACRIDINE-7-CARBOXYLIC ACIDS AND RELATED COMPOUNDS AS IMMUNOSUPPRESIVE AGENTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1993-04-28 | — | — | EP | disclosed |
| US-5190753-A | 3-phenyl-5,6-dihydrobenziciacridine-7-carboxylic acids and related compounds as immunosuppressive agents | DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1993-03-02 | — | — | US | disclosed |
| US-5135934-A | 3-PHENYL-5,6-DIHYDROBENZ(C) ACRIDINE-7-CARBOXYLIC ACIDS AND RELATED COMPOUNDS AS IMMUNOSUPPRESSIVE AGENTS | DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1992-08-04 | — | — | US | disclosed |
| WO-1992000739-A1 | 3-PHENYL-5,6-DIHYDROBENZ[C]ACRIDINE-7-CARBOXYLIC ACIDS AND RELATED COMPOUNDS AS IMMUNOSUPPRESIVE AGENTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1992-01-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060165701-A1 | Agents for the diagnosis and treatment of tumors that expose alerted proteins on the cell surface | CDC73, EPCAM, TP53 | TDP1 3327/4885ATM 2673/4885ALDH1A1 2631/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.