Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.34 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 3/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8922502 | 0.78 | CYP1A2 (0.43) | CYP1A2ALDH1A1MAPTTDP1KMT2A | |
| SCHEMBL8922506 | 0.78 | CYP1A2 (0.39) | CYP1A2ALDH1A1MAPTTDP1ACHE | |
| SCHEMBL18478 | 0.78 | TSHR (0.42) | ALDH1A1MAPTTDP1KMT2AMEN1 | |
| SCHEMBL6676890 | 0.76 | GPR35 (0.52) | CYP1A2ALDH1A1MAPTTDP1KMT2A | |
| SCHEMBL6037871 | 0.76 | TDP1 (0.38) | ALDH1A1MAPTTDP1KMT2AMEN1 | |
| SCHEMBL13836016 | 0.72 | TDP1 (0.52) | CYP1A2ALDH1A1MAPTTDP1KMT2A | |
| SCHEMBL6514635 | 0.72 | AR (0.38) | ALDH1A1MAPTTDP1KMT2AMEN1 | |
| SCHEMBL1355833 | 0.72 | ALDH1A1 (0.42) | ALDH1A1MAPTTDP1KMT2AMEN1 | |
| SCHEMBL33832 | 0.71 | TDP1 (0.46) | ALDH1A1TDP1KMT2AMEN1GPR35 | |
| SCHEMBL7136437 | 0.71 | TDP1 (0.46) | ALDH1A1TDP1KMT2AMEN1GPR35 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5041497-A | Process for preparing co-poly(amides/peptides) | ALLIED-SIGNAL INC. (US) | 1991-08-20 | — | — | US | disclosed |
| US-4970291-A | Preparation of polyamide in the presence of aryl phosphoryl azide | ALLIED-SIGNAL (US) | 1990-11-13 | — | — | US | disclosed |
| WO-1990012052-A2 | A PROCESS FOR PREPARING CO-POLY(AMIDES/PEPTIDES) | ALLIED-SIGNAL INC. (US) | 1990-10-18 | — | — | WO | disclosed |