Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.46 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.46 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.46 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.46 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3184824 | 0.82 | PLAU (0.62) | PLAUHSD17B10TDP1ALDH1A1GRIN2D | |
| SCHEMBL4365348 | 0.80 | PLAU (0.60) | PLAUHSD17B10TDP1ALDH1A1GRIN2D | |
| SCHEMBL30184963 | 0.80 | PLAU (0.60) | PLAUHSD17B10TDP1ALDH1A1GRIN2D | |
| SCHEMBL10768606 | 0.78 | PLAU (0.58) | PLAUHSD17B10TDP1ALDH1A1GRIN2D | |
| SCHEMBL30184964 | 0.78 | PLAU (0.58) | PLAUHSD17B10TDP1ALDH1A1GRIN2D | |
| SCHEMBL8013238 | 0.78 | PLAU (0.58) | PLAUHSD17B10TDP1ALDH1A1GRIN2D | |
| SCHEMBL10798681 | 0.78 | PLAU (0.58) | PLAUHSD17B10TDP1ALDH1A1GRIN2D | |
| SCHEMBL28331734 | 0.78 | PLAU (0.58) | PLAUHSD17B10TDP1ALDH1A1GRIN2D | |
| SCHEMBL16665353 | 0.78 | PLAU (0.58) | PLAUHSD17B10TDP1ALDH1A1GRIN2D | |
| SCHEMBL2374739 | 0.78 | PLAU (0.58) | PLAUHSD17B10TDP1ALDH1A1GRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4269773-A | CEPHALOSPORINS | SHIONOGI & CO., LTD. (JP) | 1981-05-26 | — | — | US | claimed |
| US-20060252051-A1 | Method for producing diverse libraries of encoded polymers | JOHN HOPKINS UNIVERSITY, THE | 2006-11-09 | — | — | US | disclosed |
| WO-2004087730-A2 | METHOD FOR PRODUCING DIVERSE LIBRARIES OF ENCODED POLYMERS | THE JOHNS HOPKINS UNIVERSITY (US) | 2004-10-14 | — | — | WO | disclosed |
| US-4269773-A | CEPHALOSPORINS | SHIONOGI & CO., LTD. (JP) | 1981-05-26 | — | — | US | disclosed |
| US-4159984-A | METAL AND PROTON DONOR | SHIONOGI & CO., LTD. (JP) | 1979-07-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060252051-A1 | Method for producing diverse libraries of encoded polymers | NSUN3, TRMT1, TARBP1 | PLAU 1743/4885HSD17B10 2185/4885TDP1 838/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.