Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 5/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | MPO | P05164 | 7/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.35 |
| ▸ | SPR | P35270 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6037892 | 0.89 | NAMPT (0.57) | NAMPTHDAC1HDAC3CYP3A4HDAC4 | |
| SCHEMBL6038340 | 0.86 | SPR (0.51) | NAMPTHDAC1HDAC3CYP3A4HDAC4 | |
| SCHEMBL6038096 | 0.85 | NAMPT (0.52) | NAMPTHDAC1HDAC3CYP3A4HDAC4 | |
| SCHEMBL6038087 | 0.84 | HDAC1 (0.54) | NAMPTHDAC1HDAC3CYP3A4HDAC4 | |
| SCHEMBL6038089 | 0.84 | MPO (0.43) | NAMPTHDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL6037966 | 0.83 | NAMPT (0.52) | NAMPTHDAC1HDAC3CYP3A4HDAC4 | |
| SCHEMBL6038113 | 0.82 | ACHE (0.51) | NAMPTCYP3A4MPORAB9ASPR | |
| SCHEMBL6038067 | 0.82 | HTR1D (0.50) | NAMPTSLC6A4MTNR1AMTNR1BPOLB | |
| SCHEMBL6038000 | 0.81 | NAMPT (0.41) | NAMPTHDAC1HDAC3CYP3A4HDAC4 | |
| SCHEMBL6038069 | 0.80 | SPR (0.49) | NAMPTMPOSLC6A4SPRMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060264415-A1 | Inhibitors of histone deacetylase | METHYLGENE INC. | 2006-11-23 | — | — | US | claimed |
| US-20060264415-A1 | Inhibitors of histone deacetylase | METHYLGENE INC. | 2006-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060264415-A1 | Inhibitors of histone deacetylase | HDAC1, HDAC3, HDAC11 | NAMPT 1262/4885HDAC1 1/4885HDAC3 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.