Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5279338 | 0.90 | GAA (0.41) | MAOBGAALMNASMN1; SMN2FFAR1 | |
| SCHEMBL6038088 | 0.87 | FFAR1 (0.42) | MAOBGAALMNASMN1; SMN2FFAR1 | |
| SCHEMBL6037903 | 0.86 | CA1 (0.49) | MEN1KMT2AALDH1A1 | |
| SCHEMBL6037981 | 0.85 | ACACB (0.40) | MAOBGAALMNASMN1; SMN2ACACB | |
| SCHEMBL5276948 | 0.85 | MMP1 (0.39) | GAALMNASMN1; SMN2FFAR1ACACB | |
| SCHEMBL5431945 | 0.82 | PTPN11 (0.47) | GAALMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL5278766 | 0.77 | LMNA (0.45) | GAALMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL6038131 | 0.77 | GLA (0.47) | GAALMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL5277017 | 0.77 | GAA (0.44) | GAALMNASMN1; SMN2MEN1KMT2A | |
| SCHEMBL26491210 | 0.77 | CA12 (0.36) | MAOBSMN1; SMN2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060264415-A1 | Inhibitors of histone deacetylase | METHYLGENE INC. | 2006-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060264415-A1 | Inhibitors of histone deacetylase | HDAC1, HDAC3, HDAC11 | MAOB 750/4885GAA 569/4885LMNA 851/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.