Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5276948 | 0.82 | MMP1 (0.39) | SMN1; SMN2GAAALDH1A1LMNAMEN1 | |
| SCHEMBL5284801 | 0.82 | ALDH1A1 (0.51) | GLAHTTSMN1; SMN2GAATP53 | |
| SCHEMBL6037903 | 0.81 | CA1 (0.49) | ALDH1A1MAPTPOLBMEN1KMT2A | |
| SCHEMBL5279338 | 0.79 | GAA (0.41) | HTTSMN1; SMN2GAAALDH1A1LMNA | |
| SCHEMBL5278766 | 0.78 | LMNA (0.45) | SMN1; SMN2GAAALDH1A1LMNA | |
| SCHEMBL6038107 | 0.77 | MAOB (0.43) | HTTSMN1; SMN2GAAALDH1A1LMNA | |
| SCHEMBL5282703 | 0.76 | SMN1; SMN2 (0.45) | HTTSMN1; SMN2GAAALDH1A1LMNA | |
| SCHEMBL6038088 | 0.76 | FFAR1 (0.42) | HTTSMN1; SMN2GAAALDH1A1LMNA | |
| SCHEMBL5280431 | 0.76 | LMNA (0.48) | SMN1; SMN2ALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL5280441 | 0.75 | ALDH1A1 (0.43) | HTTSMN1; SMN2ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060264415-A1 | Inhibitors of histone deacetylase | METHYLGENE INC. | 2006-11-23 | — | — | US | claimed |
| US-20060264415-A1 | Inhibitors of histone deacetylase | METHYLGENE INC. | 2006-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060264415-A1 | Inhibitors of histone deacetylase | HDAC1, HDAC3, HDAC11 | GLA 372/4885HTT 846/4885SMN1; SMN2 3733/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.