Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MMP13 | P45452 | 4/20 | 0.36 |
| ▸ | MMP1 | P03956 | 3/20 | 0.36 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | MMP9 | P14780 | 2/20 | 0.36 |
| ▸ | DDR2 | Q16832 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5282822 | 0.84 | HDAC1 (0.46) | HDAC1HDAC6TP53LMNARAB9A | |
| SCHEMBL5277732 | 0.84 | RAB9A (0.50) | HDAC1HDAC6TP53LMNADDR2 | |
| SCHEMBL5290863 | 0.83 | HDAC1 (0.44) | HDAC1HDAC6TP53LMNAGAA | |
| SCHEMBL6038367 | 0.83 | TP53 (0.41) | HDAC1HDAC6TP53LMNADDR2 | |
| SCHEMBL5290880 | 0.82 | TP53 (0.41) | HDAC1HDAC6TP53LMNAGAA | |
| SCHEMBL6038003 | 0.80 | TP53 (0.51) | HDAC1HDAC6TP53LMNAPOLB | |
| SCHEMBL5280650 | 0.79 | RAB9A (0.45) | HDAC1HDAC6TP53LMNARAB9A | |
| SCHEMBL5286061 | 0.79 | ALDH1A1 (0.55) | TP53LMNAGAAPOLB | |
| SCHEMBL6038116 | 0.78 | TP53 (0.39) | HDAC1HDAC6TP53LMNADDR2 | |
| SCHEMBL5282375 | 0.78 | AOC3 (0.47) | TP53LMNADDR2MAPK14RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060264415-A1 | Inhibitors of histone deacetylase | METHYLGENE INC. | 2006-11-23 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060264415-A1 | Inhibitors of histone deacetylase | HDAC1, HDAC3, HDAC11 | HDAC1 1/4885HDAC6 17/4885TP53 2551/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.