Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 6/20 | 0.36 |
| ▸ | ITGA4 | P13612 | 6/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.33 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 2/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3850595 | 0.92 | ITGB1 (0.37) | ITGB1ITGA4KEAP1NFE2L2ALDH1A1 | |
| SCHEMBL3855712 | 0.91 | ITGB1 (0.35) | ITGB1ITGA4MAPTMMP9MMP2 | |
| SCHEMBL3858699 | 0.91 | ITGB1 (0.41) | ITGB1ITGA4KEAP1NFE2L2ALDH1A1 | |
| SCHEMBL3850610 | 0.91 | ITGB1 (0.36) | ITGB1ITGA4KEAP1NFE2L2PTGER2 | |
| SCHEMBL3852799 | 0.90 | ITGB1 (0.35) | ITGB1ITGA4KEAP1NFE2L2PTGER2 | |
| SCHEMBL3855779 | 0.90 | ITGB1 (0.35) | ITGB1ITGA4KEAP1NFE2L2ALDH1A1 | |
| SCHEMBL3855348 | 0.88 | MMP2 (0.33) | MMP9MMP2 | |
| SCHEMBL3859229 | 0.88 | KEAP1 (0.33) | KEAP1NFE2L2ALDH1A1MMP9MMP2 | |
| SCHEMBL3852976 | 0.87 | MAPT (0.32) | MAPT | |
| SCHEMBL3852543 | 0.87 | HTR1A (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060004019-A1 | Steroid sparing agents and methods of using same | BIOGEN IDEC INTERNATIONAL HOLDING LTD. (BM) | 2006-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060004019-A1 | Steroid sparing agents and methods of using same | IL5, FCER2, CD40 | ITGB1 305/4885ITGA4 298/4885KEAP1 1657/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.