Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 6/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.40 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6140245 | 0.77 | ALOX15 (0.62) | HSP90AA1HSP90AB1ALOX15HSD17B10KDM4E | |
| SCHEMBL2058808 | 0.76 | ITGB1 (0.48) | ACACBHSD17B10TSHRALDH1A1 | |
| Hydrochloric Acid SCHEMBL29588252 | 0.76 | ALOX15 (0.60) | HSP90AA1HSP90AB1ALOX15HSD17B10KDM4E | |
| SCHEMBL7450749 | 0.76 | MAPT (0.48) | KDM4ETDP1ALDH1A1 | |
| SCHEMBL6710796 | 0.74 | ALOX15 (0.47) | ALOX15HSD17B10KDM4EUSP2EGFR | |
| Hydrochloric Acid SCHEMBL28514335 | 0.71 | ALDH1A1 (0.45) | ALOX15HSD17B10KDM4EUSP2EGFR | |
| SCHEMBL5108519 | 0.71 | ALDH1A1 (0.51) | ALOX15HSD17B10KDM4EUSP2EGFR | |
| SCHEMBL17774891 | 0.70 | HSP90AA1 (0.57) | HSP90AA1ALOX15HSD17B10KDM4EPTGS2 | |
| SCHEMBL5598391 | 0.70 | SLC7A5 (0.59) | SLC7A5HDAC8CA12CA1CA2 | |
| SCHEMBL2058586 | 0.70 | SLC7A5 (0.59) | SLC7A5HDAC8CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060004019-A1 | Steroid sparing agents and methods of using same | BIOGEN IDEC INTERNATIONAL HOLDING LTD. (BM) | 2006-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060004019-A1 | Steroid sparing agents and methods of using same | IL5, FCER2, CD40 | HSP90AA1 845/4885HSP90AB1 512/4885HSP90B1 1433/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.