Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.64 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.59 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.59 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | DRD1 | P21728 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10073043 | 0.79 | NAMPT (1.00) | NAMPTOPRM1TMEM97SIGMAR1L3MBTL1 | |
| SCHEMBL6038015 | 0.74 | MAPT (0.49) | NAMPTL3MBTL1KMT2AALDH1A1MAPT | |
| SCHEMBL6038182 | 0.73 | LMNA (0.68) | RAB9AMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL6037941 | 0.73 | ALDH1A1 (0.49) | NAMPTMEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL6038220 | 0.73 | LMNA (0.48) | NAMPTMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL5278266 | 0.73 | LMNA (0.48) | L3MBTL1GAAALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL8261335 | 0.73 | LMNA (0.48) | NAMPTRAB9AMEN1KMT2AGAA | |
| SCHEMBL6038095 | 0.72 | LMNA (0.64) | NAMPTL3MBTL1MEN1KMT2AGAA | |
| SCHEMBL416296 | 0.71 | HDAC1 (0.64) | NAMPTOPRM1TMEM97SIGMAR1RAB9A | |
| SCHEMBL6038074 | 0.71 | PKM (0.44) | NAMPTRAB9AGAAALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060264415-A1 | Inhibitors of histone deacetylase | METHYLGENE INC. | 2006-11-23 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060264415-A1 | Inhibitors of histone deacetylase | HDAC1, HDAC3, HDAC11 | NAMPT 1262/4885OPRM1 4082/4885TMEM97 4336/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.