SCHEMBL6038587

SCHEMBL6038587

[NH]S(=O)(=O)c1c(Cl)cc(Cl)cc1Cl

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 2/20 0.41
CA2 P00918 2/20 0.41
CA9 Q16790 1/20 0.41
ALDH1A1 P00352 4/20 0.41
TSHR P16473 4/20 0.38
HSD17B10 Q99714 2/20 0.38
CYP3A4 P08684 1/20 0.38
RECQL P46063 1/20 0.38
CNR1 P21554 1/20 0.36
CES1 P23141 2/20 0.35
DNMT1 P26358 1/20 0.34
AHR P35869 1/20 0.33
HPGD P15428 1/20 0.33
F2 P00734 1/20 0.33
PRSS1 P07477 1/20 0.33
PRSS2 P07478 1/20 0.33
PRSS3 P35030 1/20 0.33
SLC40A1 Q9NP59 1/20 0.33
ACLY P53396 1/20 0.33
SPR P35270 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6038597 0.84 RAPGEF4 (0.37) CA1CA2CA9ALDH1A1CNR1
SCHEMBL14431517 0.78 ALDH1A1 (0.45) CA1CA2CA9ALDH1A1TSHR
SCHEMBL18280205 0.76 ALDH1A1 (0.43) CA1CA2CA9ALDH1A1TSHR
SCHEMBL181647 0.76 ALDH1A1 (0.43) CA1CA2CA9ALDH1A1TSHR
SCHEMBL14532531 0.74 CA1 (0.46) CA1CA2CA9ALDH1A1TSHR
SCHEMBL1645227 0.74 CA1 (0.54) CA1CA2CA9ALDH1A1TSHR
SCHEMBL13271939 0.74 CA1 (0.41) CA1CA2CA9ALDH1A1TSHR
SCHEMBL1036705 0.74 ALDH1A1 (0.44) ALDH1A1TSHRCNR1CES1SLC40A1
SCHEMBL11155608 0.74 CA1 (0.41) CA1CA2CA9ALDH1A1TSHR
SCHEMBL3132764 0.74 ALDH1A1 (0.43) CA1CA2CA9ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060004010-A1 Ccr4 antagonist and medical use thereof ONO PHARMACEUTICAL CO., LTD. (JP) 2006-01-05 US disclosed
EP-1541563-A1 CCR4 ANTAGONIST AND MEDICINAL USE THEREOF ONO PHARMACEUTICAL CO., LTD. (JP) 2005-06-15 EP disclosed
US-4975359-A Photographic light-sensitive materials containing couplers that release diffusible dyes and DIR compounds FUJI PHOTO FILM CO., LTD. (JP) 1990-12-04 US disclosed
EP-0115303-B1 SILVER HALIDE COLOUR PHOTOGRAPHIC LIGHT-SENSITIVE MATERIAL FUJI PHOTO FILM CO., LTD. (JP) 1989-10-04 EP disclosed
EP-0174871-B1 SILVER HALIDE COLOR PHOTOGRAPHIC MATERIAL KONICA CORPORATION (JP) 1989-04-19 EP disclosed
EP-0114674-B1 SILVER HALIDE COLOR PHOTOGRAPHIC LIGHT-SENSITIVE MATERIAL FUJI PHOTO FILM CO., LTD. (JP) 1989-04-12 EP disclosed
US-4789624-A HIGH SPEED COUPLER FUJI PHOTO FILM CO., LTD. (JP) 1988-12-06 US disclosed
EP-0115305-B1 SILVER HALIDE COLOR PHOTOGRAPHIC LIGHT-SENSITIVE MATERIAL FUJI PHOTO FILM CO., LTD. (JP) 1988-06-15 EP disclosed
US-4729944-A NONDIFFUSIBLE COUPLER, IMPROVED GRANINESS AND SENSITIVITY FUJI PHOTO FILM CO., LTD. (JP) 1988-03-08 US disclosed
EP-0096873-B1 SILVER HALIDE COLOR PHOTOGRAPHIC LIGHT-SENSITIVE MATERIALS FUJI PHOTO FILM CO., LTD. (JP) 1987-12-02 EP disclosed
US-4294918-A CONTAINING A COLORLESS CYAN COLOR FORMING COUPLER FUJI PHOTO FILM CO., LTD. (JP) 1981-10-13 US disclosed
US-4283486-A DISCOLORATION INHIBITION FUJI PHOTO FILM CO., LTD. (JP) 1981-08-11 US disclosed
US-4264722-A A COLORLESS CYAN-COLOR-FORMING COUPLER COMPRISING 4-OXY-DERIVATIVES OF 1-HYDROXY-2-SEC-AMIDO-NAPHTHALENE OR BENZENE FUJI PHOTO FILM CO., LTD. (JP) 1981-04-28 US disclosed
US-4254212-A ALKOXY SUBSTITUTED SULFONYL FUJI PHOTO FILM CO., LTD. (JP) 1981-03-03 US disclosed
EP-0024033-A1 Photographic colour couplers and light-sensitive material containing them FUJI PHOTO FILM CO., LTD. (JP) 1981-02-18 EP disclosed
US-4228233-A CYAN DYE FORMING, COLORLESS COUPLER FUJI PHOTO FILM CO., LTD. (JP) 1980-10-14 US disclosed
US-4217410-A CYAN DYE COUPLER, PHOSPHATE SOLVENTS FUJI PHOTO FILM CO., LTD. (JP) 1980-08-12 US disclosed
US-4083721-A AROMATIC PRIMARY AMINE DEVELOPER FUJI PHOTO FILM CO., LTD. (JA) 1978-04-11 US disclosed
US-4072525-A COLOR PHOTOGRAPHY FUJI PHOTO FILM CO., LTD. (JA) 1978-02-07 US disclosed
US-4032345-A SILVER HALIDE MATERIALS CONTAINING PHOTOGRAPHIC COLOR COUPLERS WITH ISOTHIOCYANATO GROUPS FUJI PHOTO FILM CO., LTD. (JA) 1977-06-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060004010-A1 Ccr4 antagonist and medical use thereof CCR4, CCR1, CCR9 CA1 838/4885CA2 743/4885CA9 495/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.