SCHEMBL181647

SCHEMBL181647

O=S(=O)(Cl)c1c(Cl)cc(Cl)cc1Cl

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.43
CA1 P00915 2/20 0.43
CA2 P00918 2/20 0.43
CA9 Q16790 1/20 0.43
TSHR P16473 4/20 0.39
HSD17B10 Q99714 2/20 0.39
CYP3A4 P08684 1/20 0.39
RECQL P46063 1/20 0.39
CNR1 P21554 1/20 0.37
CES1 P23141 2/20 0.37
DNMT1 P26358 1/20 0.35
AHR P35869 1/20 0.35
HPGD P15428 1/20 0.35
F2 P00734 1/20 0.34
PRSS1 P07477 1/20 0.34
PRSS2 P07478 1/20 0.34
PRSS3 P35030 1/20 0.34
ACLY P53396 1/20 0.34
SLC40A1 Q9NP59 1/20 0.34
TRPV4 Q9HBA0 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1510464 0.84 CA1 (0.38) ALDH1A1CA1CA2CA9TSHR
SCHEMBL544443 0.84 CA1 (0.41) ALDH1A1CA1CA2CA9TSHR
SCHEMBL21550409 0.84 TSHR (0.48) ALDH1A1CA1CA2CA9TSHR
SCHEMBL788180 0.84 RAPGEF4 (0.38) ALDH1A1CA1CA2CA9RECQL
SCHEMBL14431517 0.80 ALDH1A1 (0.45) ALDH1A1CA1CA2CA9TSHR
SCHEMBL1036314 0.79 NMT1 (0.42) CA1CA2CA9ACLYTRPV4
SCHEMBL1077563 0.79 CYP3A4 (0.48) ALDH1A1CA1CA2CA9TSHR
SCHEMBL4512524 0.79 CA1 (0.35) ALDH1A1CA1CA2TSHRRECQL
SCHEMBL10958575 0.79 HSD17B10 (0.48) ALDH1A1CA1CA2TSHRHSD17B10
SCHEMBL4476920 0.79 TRPV4 (0.35) CA1CA2CA9ACLYTRPV4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 240 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107376875-A A kind of preparation and application of the beta cyclodextrin porous material with quick adsorption ability 湖南理工学院 2017-11-24 CN claimed
CN-104678028-A Pretreatment and detection method for biogen amine neurotransmitter and detection kit INST PHARM & TOXICOLOGY AMMS 2015-06-03 CN claimed
EP-1377589-B1 OXAZOLYL-PYRAZOLE DERIVATIVES AS KINASE INHIBITORS PHARMACIA ITALIA SPA (IT) 2005-09-07 EP claimed
US-12606522-B2 Sulfinylaminobenzamide and sulfonylaminobenzamide derivatives ORSOBIO, INC. (US) 2026-04-21 US disclosed
EP-3735975-B1 ERTUGLIFLOZIN FOR USE IN TREATING HEART FAILURE IN PATIENTS WITH DIABETES MERCK SHARP & DOHME LLC (US) 2025-12-03 EP disclosed
US-20250115687-A1 PRODUCTION METHOD FOR SOLID CATALYST COMPONENT FOR POLYMERIZING OLEFINS, AND CATALYST FOR POLYMERIZAING OLEFINS FORMOSA PLASTICS CORP USA (US) 2025-04-10 US disclosed
CN-115368280-B Preparation method and application of novel thermosensitive color developing agent 康爱特维迅(蓬莱)化学有限公司 2025-04-04 CN disclosed
CN-119390708-A Novel curcumenol derivative and synthetic method and application thereof 天津中医药大学 2025-02-07 CN disclosed
US-20250004377-A1 ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE FILM, PATTERN FORMING METHOD, AND METHOD FOR PRODUCING ELECTRONIC DEVICE FUJIFILM CORPORATION (JP) 2025-01-02 US disclosed
US-20240409508-A1 SULFINYLAMINOBENZAMIDE AND SULFONYLAMINOBENZAMIDE DERIVATIVES ORSOBIO, INC. 2024-12-12 US disclosed
US-12164230-B2 Actinic ray-sensitive or radiation-sensitive resin composition, actinic ray-sensitive or radiation-sensitive film, pattern forming method, method for manufacturing electronic device, and compound FUJIFILM CORPORATION (JP) 2024-12-10 US disclosed
US-6015812-A N-(arylsulphonyl)amino acid derivatives having bradykinin receptor affinity SANOFI-SYNTHELABO (FR) 2000-01-18 US disclosed
WO-1999031092-A1 BENZAMINE DERIVATIVES MERCK PATENT GMBH (DE) 1999-06-24 WO disclosed
CN-1037568-C Phosphosulfonate herbicides ROHM & HAAS (US) 1998-03-04 CN disclosed
EP-0511826-B1 Phosphosulfonate herbicides ROHM & HAAS (US) 1997-07-16 EP disclosed
US-5500405-A Phosphosulfonate herbicides ROHM AND HAAS COMPANY (US) 1996-03-19 US disclosed
US-5272128-A Phosphosulfonate herbicides ROHM AND HAAS COMPANY (US) 1993-12-21 US disclosed
EP-0511826-A2 Phosphosulfonate herbicides ROHM AND HAAS COMPANY (US) 1992-11-04 EP disclosed
US-4113463-A BENZENESULFONAMIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1978-09-12 US disclosed
US-4070176-A WITH A BENZENESULFONAMIDE SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1978-01-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12606522-B2 Sulfinylaminobenzamide and sulfonylaminobenzamide derivatives NR3C2, NR5A1, SRD5A2 ALDH1A1 1507/4885CA1 3778/4885CA2 3086/4885
US-20240409508-A1 SULFINYLAMINOBENZAMIDE AND SULFONYLAMINOBENZAMIDE DERIVATIVES STS, SULT2A1, SCN2B ALDH1A1 245/4885CA1 2349/4885CA2 1775/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.