SCHEMBL603909

SCHEMBL603909

CC(C)(C)c1nc(-c2nc(=O)o[nH]2)cc(C(F)(F)F)n1

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
DRD3 P35462 20/20 0.35
DRD2 P14416 19/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL600563 0.90 HPGD (0.34)
SCHEMBL604061 0.83 SDHB (0.33)
SCHEMBL601836 0.80 HSD17B10 (0.51)
SCHEMBL603661 0.80 MEN1 (0.36)
SCHEMBL601205 0.80 CYP3A4 (0.33) DRD3DRD2
SCHEMBL603910 0.77 RARB (0.39) DRD3DRD2
SCHEMBL601265 0.77 LMNA (0.50)
SCHEMBL602765 0.76 LCAT (0.36) DRD3DRD2
SCHEMBL18107 0.75 CA2 (0.39)
SCHEMBL2338989 0.71 RAD51 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120041009-A1 PYRIMIDINE COMPOUND AND ITS USE IN PEST CONTROL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-02-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120041009-A1 PYRIMIDINE COMPOUND AND ITS USE IN PEST CONTROL TYMP, DPYD, TYMS DRD3 4072/4885DRD2 2455/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.