Acetic Acid

Acetic Acid

SCHEMBL6039286

CC(=O)[O-].CCC[N+](C)(C)N

nearest known ligand 0.40

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Known targets — ChEMBL curated mechanism

ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.40
BBOX1 O75936 4/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C19 P33261 1/20 0.39
FFAR3 O14843 2/20 0.36
HDAC3 O15379 2/20 0.36
HDAC1 Q13547 2/20 0.36
HDAC2 Q92769 2/20 0.36
HDAC8 Q9BY41 2/20 0.36
CES1 P23141 2/20 0.33
CES2 O00748 1/20 0.33
CYP3A4 P08684 2/20 0.32
TSHR P16473 2/20 0.32
NFKB1 P19838 2/20 0.32
NPSR1 Q6W5P4 2/20 0.32
CPT2 P23786 1/20 0.31
CPT1A P50416 1/20 0.31
ACHE P22303 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glycine SCHEMBL290022 0.86 BBOX1 (0.41) CA1BBOX1CYP2D6CYP2C19FFAR3
L-Lactic Acid SCHEMBL27743481 0.82 TSHR (0.37) CA1BBOX1CYP2D6CYP2C19FFAR3
SCHEMBL352085 0.81
Acetic Acid SCHEMBL27957649 0.79 DNM1 (0.46) CA1BBOX1FFAR3HDAC3HDAC1
Acetic Acid SCHEMBL3684341 0.79 CA1 (0.44) CA1BBOX1CYP2C19FFAR3HDAC3
Acetic Acid SCHEMBL557807 0.79 CA1 (0.44) CA1BBOX1FFAR3HDAC3HDAC1
Hydrochloric Acid SCHEMBL4850830 0.78
Citric Acid SCHEMBL27511805 0.76 CA4 (0.55) BBOX1FFAR3HDAC3HDAC1HDAC2
Tetrapropylammonium SCHEMBL109162 0.76 SLC22A1 (0.59) CA1BBOX1FFAR3HDAC3HDAC1
Acetic Acid SCHEMBL10911055 0.75 CA1 (0.40) CA1BBOX1FFAR3HDAC3HDAC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7125825-B2 Amidoamine salt-based viscosifying agents and methods of use TOMAH PRODUCTS, INC. (US) 2006-10-24 US disclosed
WO-2004096942-A1 AMIDOAMINE SALT-BASED VISCOSIFYING AGENTS AND METHOD OF USE TOMAH PRODUCTS, INC. (US) 2004-11-11 WO disclosed
US-20040214725-A1 Amidoamine salt-based viscosifying agents and methods of use TOMAH PRODUCTS, INC. 2004-10-28 US disclosed
US-6361940-B1 IMMOBILIZATION; GENETIC ENGINEERING QIAGEN GENOMICS, INC. 2002-03-26 US disclosed