Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1A | P07327 | 11/20 | 0.41 |
| ▸ | ADH1C | P00326 | 8/20 | 0.41 |
| ▸ | ADH4 | P08319 | 2/20 | 0.39 |
| ▸ | ADH1B | P00325 | 2/20 | 0.33 |
| ▸ | ADH7 | P40394 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18841480 | 0.83 | ADH1A (0.48) | ADH1AADH1CADH4ADH1BADH7 | |
| SCHEMBL29958136 | 0.83 | ADH1A (0.38) | ADH1AADH1CADH4ADH1BCYP2D6 | |
| SCHEMBL29951154 | 0.79 | ADH1A (0.35) | ADH1AADH1CADH4 | |
| SCHEMBL8159835 | 0.78 | CYP2D6 (0.39) | ADH1AADH1CCYP2D6CYP2C9HSD17B10 | |
| SCHEMBL29952616 | 0.77 | ADH1A (0.52) | ADH1AADH1CADH4ADH1BADH7 | |
| SCHEMBL29957210 | 0.76 | ADH1A (0.55) | ADH1AADH1CADH4ADH1BADH7 | |
| SCHEMBL6039331 | 0.76 | CYP2D6 (0.31) | ADH1AADH1CCYP2D6CYP2C9HSD17B10 | |
| SCHEMBL29951894 | 0.73 | ADH1C (0.31) | ADH1AADH1CADH4 | |
| SCHEMBL14067386 | 0.70 | ADH1A (0.43) | ADH1AADH1CCYP2D6CYP2C9HSD17B10 | |
| SCHEMBL6039748 | 0.70 | ADH1A (0.44) | ADH1AADH1CADH4ADH1BADH7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006038001-A1 | AMINOPYRIMIDINE DERIVATIVES AS JNK INHIBITORS | CELLTECH R & D LIMITED (GB) | 2006-04-13 | — | — | WO | disclosed |