Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 3/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CHKA | P35790 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6039343 | 0.97 | — | — | |
| SCHEMBL1821635 | 0.77 | CA2 (0.38) | ALDH1A1CA2CA1TSHRCHKA | |
| SCHEMBL11101489 | 0.74 | ALDH1A1 (0.39) | ALDH1A1HPGDMEN1KMT2AMMP1 | |
| SCHEMBL319864 | 0.74 | ALDH1A1 (0.41) | L3MBTL1ALDH1A1NPC1F2HPGD | |
| SCHEMBL17710771 | 0.72 | ALDH1A1 (0.38) | L3MBTL1ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL9253930 | 0.72 | ALDH1A1 (0.38) | L3MBTL1ALDH1A1F2HPGDMMP1 | |
| SCHEMBL16935754 | 0.72 | L3MBTL1 (0.35) | L3MBTL1ALDH1A1MAPTGAAPOLB | |
| SCHEMBL22684280 | 0.71 | — | — | |
| SCHEMBL17731151 | 0.70 | ALDH1A1 (0.48) | ALDH1A1NPC1HPGDMEN1KMT2A | |
| SCHEMBL30166170 | 0.70 | NPC1 (0.39) | L3MBTL1ALDH1A1NPC1HPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006038001-A1 | AMINOPYRIMIDINE DERIVATIVES AS JNK INHIBITORS | CELLTECH R & D LIMITED (GB) | 2006-04-13 | — | — | WO | disclosed |