Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11646552 | 0.86 | — | — | |
| SCHEMBL28747406 | 0.85 | HSD17B10 (0.31) | HSD17B10 | |
| SCHEMBL3668425 | 0.78 | — | — | |
| SCHEMBL28863033 | 0.75 | — | — | |
| SCHEMBL529335 | 0.75 | — | — | |
| SCHEMBL11451621 | 0.74 | — | — | |
| SCHEMBL1447629 | 0.74 | ALDH1A1 (0.35) | ALDH1A1POLB | |
| SCHEMBL1448087 | 0.74 | ALDH1A1 (0.35) | ALDH1A1POLB | |
| SCHEMBL1720282 | 0.72 | HRH3 (0.46) | HSD17B10MAPTALDH1A1POLB | |
| SCHEMBL378009 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107001358-A | Adjust the new pyridine hepyramine compound of istone lysine demethylase (KDM) catalytic activity | 东亚ST株式会社 | 2017-08-01 | — | — | CN | claimed |
| CN-107001358-A | Adjust the new pyridine hepyramine compound of istone lysine demethylase (KDM) catalytic activity | 东亚ST株式会社 | 2017-08-01 | — | — | CN | disclosed |
| WO-2006038001-A1 | AMINOPYRIMIDINE DERIVATIVES AS JNK INHIBITORS | CELLTECH R & D LIMITED (GB) | 2006-04-13 | — | — | WO | disclosed |