Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | CASR | P41180 | 2/20 | 0.39 |
| ▸ | FLT3 | P36888 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL417541 | 0.80 | ALOX5 (0.49) | ALOX5BRD4KDM4ELMNATP53 | |
| SCHEMBL831428 | 0.78 | ALOX5 (0.51) | ALOX5BRD4KDM4ELMNATP53 | |
| SCHEMBL3663172 | 0.75 | ALOX5 (0.55) | ALOX5BRD4KDM4ELMNATP53 | |
| SCHEMBL4985929 | 0.75 | ALOX5 (0.54) | ALOX5BRD4KDM4ELMNATP53 | |
| SCHEMBL30733359 | 0.75 | ALOX5 (0.54) | ALOX5BRD4KDM4ELMNATP53 | |
| SCHEMBL336690 | 0.75 | ALOX5 (0.54) | ALOX5BRD4KDM4ELMNATP53 | |
| SCHEMBL9206908 | 0.74 | ALOX5 (0.48) | ALOX5BRD4KDM4ELMNATP53 | |
| SCHEMBL3229357 | 0.72 | ALOX5 (0.55) | ALOX5BRD4KDM4ELMNATP53 | |
| SCHEMBL19981811 | 0.72 | ALOX5 (0.51) | ALOX5BRD4KDM4ELMNATP53 | |
| SCHEMBL1706542 | 0.72 | ALOX5 (0.51) | ALOX5BRD4KDM4ELMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006038001-A1 | AMINOPYRIMIDINE DERIVATIVES AS JNK INHIBITORS | CELLTECH R & D LIMITED (GB) | 2006-04-13 | — | — | WO | disclosed |