Sugi Predict

Sugi Predict / Compounds / SCHEMBL336690

SCHEMBL336690

SCHEMBL336690

CC(C)c1cc2ccccc2[nH]1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALOX5 P09917 1/20 0.54
▸ AOC3 Q16853 2/20 0.48
▸ BRD4 O60885 1/20 0.47
▸ KDM4E B2RXH2 7/20 0.46
▸ LMNA P02545 2/20 0.46
▸ TP53 P04637 1/20 0.46
▸ L3MBTL1 Q9Y468 1/20 0.46
▸ RAB9A P51151 3/20 0.45
▸ NPC1 O15118 2/20 0.45
▸ LOXL2 Q9Y4K0 1/20 0.44
▸ FLT3 P36888 1/20 0.44
▸ CYP2A6 P11509 1/20 0.44
▸ MAPT P10636 4/20 0.43
▸ HSD17B10 Q99714 2/20 0.43
▸ ALDH1A1 P00352 2/20 0.43
▸ DAO P14920 2/20 0.42
▸ HPGD P15428 2/20 0.42
▸ SRD5A2 P31213 1/20 0.42
▸ DDO Q99489 1/20 0.42
▸ TSHR P16473 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30733359 1.00 ALOX5 (0.54) ALOX5AOC3BRD4KDM4ELMNA
SCHEMBL4985929 0.87 ALOX5 (0.54) ALOX5AOC3BRD4KDM4ELMNA
Alanine SCHEMBL28826582 0.85 ALOX5 (0.57) ALOX5AOC3BRD4KDM4ELMNA
SCHEMBL3663172 0.83 ALOX5 (0.55) ALOX5AOC3BRD4KDM4ELMNA
SCHEMBL31299796 0.83 ALOX5 (0.55) ALOX5AOC3BRD4KDM4ELMNA
SCHEMBL3229357 0.83 ALOX5 (0.55) ALOX5AOC3BRD4KDM4ELMNA
SCHEMBL6141109 0.83 ALOX5 (0.55) ALOX5AOC3BRD4KDM4ELMNA
SCHEMBL19981811 0.83 ALOX5 (0.51) ALOX5AOC3BRD4KDM4ELMNA
SCHEMBL1706542 0.83 ALOX5 (0.51) ALOX5AOC3BRD4KDM4ELMNA
SCHEMBL8598079 0.82 AOC3 (0.52) ALOX5AOC3BRD4KDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 591 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118239981-A Phosphonite ligand, catalyst and application thereof in hydroformylation reaction 万华化学集团股份有限公司 2024-06-25 — — CN claimed
CN-108026162-A Cystine knot scaffold platform 豪夫迈·罗氏有限公司 2018-05-11 — — CN claimed
US-20250188060-A1 ALPHA1A-ADRENERGIC RECEPTOR AGONISTS AND METHODS OF USE CURASEN THERAPEUTICS, INC. 2025-06-12 — — US disclosed
EP-4499070-A1 ALPHA 1A-ADRENERGIC RECEPTOR AGONISTS AND METHODS OF USE Curasen Therapeutics, Inc. (US) 2025-02-05 — — EP disclosed
CN-118239981-A Phosphonite ligand, catalyst and application thereof in hydroformylation reaction 万华化学集团股份有限公司 2024-06-25 — — CN disclosed
WO-2024124287-A1 COMPOUNDS FOR TREATING VIRAL INFECTION THE WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH (AU) 2024-06-20 — — WO disclosed
US-11912714-B2 Spiropyrrolidine derived antiviral agents ENANTA PHARMACEUTICALS, INC. (US) 2024-02-27 — — US disclosed
US-11912714-B2 Spiropyrrolidine derived antiviral agents ENANTA PHARMACEUTICALS, INC. (US) 2024-02-27 — — US disclosed
WO-2024028364-A1 ARYL-TRIAZOLYL AND RELATED GPR84 ANTAGONISTS AND USES THEREOF Liminal Biosciences Limited (GB) 2024-02-08 — — WO disclosed
US-20240018119-A1 CARBOXAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING MENTAL ILLNESS TRINEURO (KR) 2024-01-18 — — US disclosed
US-20240018125-A1 CYCLIC ISOTHIOUREA DERIVATIVES AS CXCR4 MODULATORS ERMIUM THERAPEUTICS (FR) 2024-01-18 — — US disclosed
US-4322352-A Indolyl phthalide compounds STERLING DRUG INC. (US) 1982-03-30 — — US disclosed
US-4307018-A CHROMOGENS FOR COPYING SYSTEMS STERLING DRUG INC. (US) 1981-12-22 — — US disclosed
US-4257954-A INDOLYL-PHENYLSULFONYL-PHENYL METHANE STERLING DRUG INC. (US) 1981-03-24 — — US disclosed
US-4251446-A COLOR PRECURSORS STERLING DRUG INC. (US) 1981-02-17 — — US disclosed
US-4217357-A Inhibition of thromboxane synthetase with 3-(imidazol-1-ylalkyl)indoles PFIZER INC. (US) 1980-08-12 — — US disclosed
US-4189171-A PRESSURE SENSITIVE, THERMAL AND HECTOGRAPHIC SYSTEMS STERLING DRUG INC. (US) 1980-02-19 — — US disclosed
EP-0003901-A2 3-(Imidazol-1-ylalkyl)indoles as selective inhibitors of thromboxane synthetase,pharmaceutical compositions thereof, and methods for preparing them Pfizer Limited (GB) 1979-09-05 — — EP disclosed
US-4122278-A INTERMEDIATES FOR DYES PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1978-10-24 — — US disclosed
US-4101540-A USEFUL FOR DYEING ACRYLONITRILE POLYMERS OR ACID-MODIFIED POLYESTERS OR POLYAMIDES PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1978-07-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240018125-A1 CYCLIC ISOTHIOUREA DERIVATIVES AS CXCR4 MODULATORS CXCR4, CXCR1, CXCL12 ALOX5 3748/4885AOC3 4831/4885BRD4 1647/4885
US-20250188060-A1 ALPHA1A-ADRENERGIC RECEPTOR AGONISTS AND METHODS OF USE ADRB1, ADRA1A, ADRA1D ALOX5 1501/4885AOC3 777/4885BRD4 4265/4885
US-20240018119-A1 CARBOXAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT FOR PREVENTING OR TREATING MENTAL ILLNESS MAOA, DRD2, MAOB ALOX5 1744/4885AOC3 1650/4885BRD4 343/4885
US-11912714-B2 Spiropyrrolidine derived antiviral agents ACE, ACE2, PKD1 ALOX5 2293/4885AOC3 4484/4885BRD4 1620/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.