SCHEMBL861278

SCHEMBL861278

CC(C)(C)OC(=O)N1CCC1

nearest known ligand 0.64

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.64
SMN1; SMN2 Q16637 1/20 0.64
HPGD P15428 1/20 0.62
MEN1 O00255 3/20 0.58
KMT2A Q03164 3/20 0.58
EPHX1 P07099 1/20 0.54
CTSK P43235 1/20 0.52
MAPT P10636 2/20 0.51
RECQL P46063 1/20 0.50
ALDH1A1 P00352 1/20 0.47
PREP P48147 1/20 0.47
EPHX2 P34913 1/20 0.47
GPR119 Q8TDV5 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16612394 0.98 USP2 (0.62) USP2SMN1; SMN2HPGDMEN1KMT2A
Methyl Alcohol SCHEMBL27463839 0.98 USP2 (0.62) USP2SMN1; SMN2HPGDMEN1KMT2A
SCHEMBL27893273 0.98 USP2 (0.62) USP2SMN1; SMN2HPGDMEN1KMT2A
Ammonia Solution, Strong SCHEMBL28133562 0.98 USP2 (0.62) USP2SMN1; SMN2HPGDMEN1KMT2A
Iodide SCHEMBL15174787 0.98 USP2 (0.62) USP2SMN1; SMN2HPGDMEN1KMT2A
SCHEMBL7858182 0.95 HPGD (0.68) USP2SMN1; SMN2HPGDMEN1KMT2A
SCHEMBL5053 0.95 HPGD (0.68) USP2SMN1; SMN2HPGDMEN1KMT2A
Acetic Acid SCHEMBL3768719 0.94 USP2 (0.58) USP2SMN1; SMN2HPGDMEN1KMT2A
SCHEMBL19852529 0.93 HPGD (0.71) USP2SMN1; SMN2HPGDMEN1KMT2A
SCHEMBL60470 0.93 HPGD (0.71) USP2SMN1; SMN2HPGDMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1066 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3634959-B1 QUINOLINE DERIVATIVES FOR TREATING INFECTIONS WITH HELMINTHS ELANCO ANIMAL HEALTH GMBH (DE) 2025-02-26 EP claimed
CN-119497712-A Indane derivatives as MALT1 inhibitors 希四克斯探索有限公司 2025-02-21 CN claimed
CN-113924146-B Novel compounds and pharmaceutical compositions thereof for the treatment of diseases 加拉帕戈斯股份有限公司 2024-12-10 CN claimed
CN-119080663-A Efficient low-cost synthesis method of azetidine hydrochloride 南宁师范大学 2024-12-06 CN claimed
CN-118541362-A Pyridazinylamino derivatives as ALK5 inhibitors 奇斯药制品公司 2024-08-23 CN claimed
CN-107531698-B Fused bicyclic heteroaryl derivatives having activity as PHD inhibitors 武田药品工业株式会社 2024-08-13 CN claimed
CN-111132977-B Quinoline derivatives for the treatment of helminth infections 礼蓝动物保健有限公司 2024-07-23 CN claimed
US-20240108654-A1 COMBINATION OF A T CELL THERAPY AND A DGK INHIBITOR JUNO THERAPEUTICS, INC. (US) 2024-04-04 US claimed
CN-113423711-B Thieno [3,2-B ] pyridine derivatives as UDP glycosyltransferase inhibitors and methods of use thereof 建新公司 2024-03-15 CN claimed
WO-2024054944-A1 COMBINATION OF A T CELL THERAPY AND CONTINUOUS OR INTERMITTENT DGK INHIBITOR DOSING JUNO THERAPEUTICS, INC. (US) 2024-03-14 WO claimed
CN-104140387-B A kind of preparation method of N-tertbutyloxycarbonyl-azetidine aromatic ether/heteroaromatic ether compound TETRANOV PHARMACY STOCK INC. (CN) 2016-11-30 CN claimed
EP-1794129-B1 Synthesis by chiral diamine-mediated asymmetric alkylation JANSSEN PHARMACEUTICA NV (BE) 2015-12-30 EP claimed
CN-104140387-A Preparation method for N-tert-butyloxycarboryl-azetidine aromatic ether/aromatic heterocyclic ether compounds TETRANOV BIOPHARM INC 2014-11-12 CN claimed
CN-102264736-B Substituted pyrazolo [1,5-a ] pyrimidine compounds as TRK kinase inhibitors ARRAY BIOPHARMA INC 2013-08-14 CN claimed
CN-101883762-A Benzothiazoles as modulators of growth hormone releasing hormone receptors ASTRAZENECA AB 2010-11-10 CN claimed
EP-1794129-A4 SYNTHESIS BY CHIRAL DIAMINE-MEDIATED ASYMMETRIC ALKYLATION JANSSEN PHARMACEUTICA NV (BE) 2009-09-02 EP claimed
US-7402670-B2 Synthesis by chiral diamine-mediated asymmetric alkylation JANSSEN PHARMACEUTICA, N.V. (BE) 2008-07-22 US claimed
EP-1794129-A2 SYNTHESIS BY CHIRAL DIAMINE-MEDIATED ASYMMETRIC ALKYLATION JANSSEN PHARMACEUTICA N.V. (BE) 2007-06-13 EP claimed
WO-2006039383-A2 SYNTHESIS BY CHIRAL DIAMINE-MEDIATED ASYMMETRIC ALKYLATION JANSSEN PHARMACEUTICA N.V. (BE) 2006-04-13 WO claimed
US-20060069250-A1 Synthesis by chiral diamine-mediated asymmetric alkylation DENG XIAOHU 2006-03-30 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060069250-A1 Synthesis by chiral diamine-mediated asymmetric alkylation SRM, SMOX, DDC USP2 1919/4885SMN1; SMN2 3550/4885HPGD 2209/4885
US-20240108654-A1 COMBINATION OF A T CELL THERAPY AND A DGK INHIBITOR DGKG, DGKA, DGKI USP2 3864/4885SMN1; SMN2 4303/4885HPGD 3981/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.