⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14231351 | 0.93 | CASP2 (0.63) | — | |
| SCHEMBL5501338 | 0.91 | CASP2 (0.67) | — | |
| SCHEMBL8973921 | 0.91 | CASP2 (0.67) | — | |
| SCHEMBL935157 | 0.91 | CASP2 (0.67) | — | |
| SCHEMBL933644 | 0.91 | CASP2 (0.67) | — | |
| SCHEMBL934477 | 0.91 | CASP2 (0.67) | — | |
| SCHEMBL28806490 | 0.91 | CASP2 (0.67) | — | |
| SCHEMBL10050997 | 0.85 | — | — | |
| SCHEMBL3465519 | 0.83 | — | — | |
| SCHEMBL1927840 | 0.82 | ALDH1A1 (0.59) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118667812-A | Compositions and methods for treating muscular atrophy and tonic muscular dystrophy | 艾维迪提生物科学公司 | 2024-09-20 | — | — | CN | disclosed |
| CN-118638787-A | Compositions and methods for treating muscular atrophy and tonic muscular dystrophy | 艾维迪提生物科学公司 | 2024-09-13 | — | — | CN | disclosed |
| CN-118638788-A | Compositions and methods for treating muscular atrophy and tonic muscular dystrophy | 艾维迪提生物科学公司 | 2024-09-13 | — | — | CN | disclosed |
| CN-111902148-B | Compositions and methods for treating muscular atrophy and tonic muscular dystrophy | 艾维迪提生物科学公司 | 2024-07-05 | — | — | CN | disclosed |
| CN-118267396-A | Nucleic acid-polypeptide compositions and uses thereof | 艾维迪提生物科学公司 | 2024-07-02 | — | — | CN | disclosed |
| CN-118265544-A | Compositions and methods for treating facial shoulder brachial muscular dystrophy | 艾维迪提生物科学公司 | 2024-06-28 | — | — | CN | disclosed |
| CN-111655268-B | Nucleic acid-polypeptide compositions and uses thereof | 艾维迪提生物科学公司 | 2024-03-26 | — | — | CN | disclosed |
| EP-4262811-A1 | TREATMENT WITH TUMOR INFILTRATING LYMPHOCYTE THERAPIES IN COMBINATION WITH CTLA-4 AND PD-1 INHIBITORS | Iovance Biotherapeutics, Inc. (US) | 2023-10-25 | — | — | EP | disclosed |
| US-20230270876-A1 | SPECIFIC SITES FOR MODIFYING ANTIBODIES TO MAKE IMMUNOCONJUGATES | NOVARTIS AG (CH) | 2023-08-31 | — | — | US | disclosed |
| CN-115666589-A | Compositions and methods for treating facioscapulohumeral muscular dystrophy | 艾维迪提生物科学公司 | 2023-01-31 | — | — | CN | disclosed |
| WO-2014116596-A1 | METHODS FOR OPTIMIZING DOMAIN STABILITY OF BINDING PROTEINS | ABBVIE, INC. (US) | 2014-07-31 | — | — | WO | disclosed |
| US-20140065171-A1 | Site-Specific Labeling Methods and Molecules Produced Thereby | NOVARTIS INTERNATIONAL PHARMACEUTICAL LTD. (BM) | 2014-03-06 | — | — | US | disclosed |
| WO-2013173756-A1 | A METHOD FOR QUANTIFYING PROTEINS AND ISOFORMS THEREOF | UNIVERSITY OF NORTH DAKOTA (US) | 2013-11-21 | — | — | WO | disclosed |
| US-20110237503-A1 | NOVEL PEPTIDES AND METHODS FOR THEIR PREPARATION AND USE | ELI LILLY AND COMPANY (US) | 2011-09-29 | — | — | US | disclosed |
| US-20060134103-A1 | Compounds and molecular complexes comprising multiple binding regions directed to transcytotic ligands | HAWLEY STEPHEN B | 2006-06-22 | — | — | US | disclosed |
| US-20060099150-A1 | Compositions and methods for the transport of biologically active agents across cellular barriers | HOUSTON L L | 2006-05-11 | — | — | US | disclosed |
| US-20050100543-A1 | Multivalent carriers of bi-specific antibodies | IMMUNOMEDICS, INC. (US) | 2005-05-12 | — | — | US | disclosed |
| EP-1034303-A1 | METHODS OF DETECTING POLYNUCLEOTIDE ANALYTES | Diasorin International Inc. (US) | 2000-09-13 | — | — | EP | disclosed |
| WO-1999028503-A1 | METHODS OF DETECTING POLYNUCLEOTIDE ANALYTES | DIASORIN INTERNATIONAL INC. (US) | 1999-06-10 | — | — | WO | disclosed |
| CN-1083485-A | Benzo thia azepine and benzo oxa-azepine derivatives | PFIZER (US) | 1994-03-09 | — | — | CN | disclosed |