SCHEMBL5501338

SCHEMBL5501338

CCCCCCCCCCCCCCCCNC(=O)CI

nearest known ligand 0.67

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CASP2 P42575 1/20 0.67
NAAA Q02083 1/20 0.62
EPHX1 P07099 8/20 0.61
FAAH O00519 4/20 0.56
MEN1 O00255 1/20 0.54
KMT2A Q03164 1/20 0.54
ZDHHC20 Q5W0Z9 1/20 0.52
ZDHHC2 Q9UIJ5 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL933644 1.00 CASP2 (0.67) CASP2NAAAEPHX1FAAHMEN1
SCHEMBL934477 1.00 CASP2 (0.67) CASP2NAAAEPHX1FAAHMEN1
SCHEMBL28806490 1.00 CASP2 (0.67) CASP2NAAAEPHX1FAAHMEN1
SCHEMBL935157 1.00 CASP2 (0.67) CASP2NAAAEPHX1FAAHMEN1
SCHEMBL8973921 1.00 CASP2 (0.67) CASP2NAAAEPHX1FAAHMEN1
SCHEMBL14231351 0.98 CASP2 (0.63) CASP2NAAAEPHX1FAAHMEN1
SCHEMBL6040899 0.91
SCHEMBL1927840 0.89 ALDH1A1 (0.59) CASP2NAAAEPHX1FAAHMEN1
SCHEMBL1927654 0.89 ALDH1A1 (0.59) CASP2NAAAEPHX1FAAHMEN1
SCHEMBL18888843 0.86 FAAH (0.65) CASP2NAAAFAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0537178-B2 NUCLEOTIDE SEQUENCE OF SOYBEAN STEAROYL-ACP DESATURASE GENE DU PONT (US) 2007-06-13 EP disclosed
EP-0563191-B2 NUCLEOTIDE SEQUENCES OF SOYBEAN ACYL-ACP THIOESTERASE GENES DU PONT (US) 2000-01-19 EP disclosed
US-5945585-A HYBRIDIZATION OF NUCLEIC ACID FRAGMENTS AND PROTEINS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1999-08-31 US disclosed
US-5760206-A TRANSFORMING PLANT CELLS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1998-06-02 US disclosed
US-5530186-A GENETIC ENGINEERING E. I. DU PONT DE NEMOURS AND COMPANY (US) 1996-06-25 US disclosed
US-5500361-A CONTROLLING AMOUNT OF PALMITIC AND STEARIC ACIDS PRODUCED BY PLANT E. I. DU PONT DE NEMOURS AND COMPANY (US) 1996-03-19 US disclosed
EP-0563191-B1 NUCLEOTIDE SEQUENCES OF SOYBEAN ACYL-ACP THIOESTERASE GENES DU PONT (US) 1995-10-04 EP disclosed
EP-0667906-A1 $g(b)-KETOACYL-ACP SYNTHETASE II GENES FROM PLANTS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1995-08-23 EP disclosed
US-5443974-A Transforming plants to control levels of saturated and unsaturated fatty acids E. I. DU PONT DE NEMOURS AND COMPANY (US) 1995-08-22 US disclosed
EP-0537178-B1 NUCLEOTIDE SEQUENCE OF SOYBEAN STEAROYL-ACP DESATURASE GENE DU PONT (US) 1994-08-31 EP disclosed
EP-0563191-A1 NUCLEOTIDE SEQUENCES OF SOYBEAN ACYL-ACP THIOESTERASE GENES. DU PONT (US) 1993-10-06 EP disclosed
WO-1993010240-A1 β-KETOACYL-ACP SYNTHETASE II GENES FROM PLANTS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1993-05-27 WO disclosed
EP-0537178-A1 NUCLEOTIDE SEQUENCE OF SOYBEAN STEAROYL-ACP DESATURASE GENE. DU PONT (US) 1993-04-21 EP disclosed
WO-1992011373-A1 NUCLEOTIDE SEQUENCES OF SOYBEAN ACYL-ACP THIOESTERASE GENES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-07-09 WO disclosed
WO-1991018985-A1 NUCLEOTIDE SEQUENCE OF SOYBEAN STEAROYL-ACP DESATURASE GENE E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-12-12 WO disclosed