Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR3 | P25089 | 1/20 | 0.51 |
| ▸ | FPR2 | P25090 | 1/20 | 0.51 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.50 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.47 |
| ▸ | FEN1 | P39748 | 1/20 | 0.47 |
| ▸ | DPP4 | P27487 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.45 |
| ▸ | HRH2 | P25021 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.44 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.44 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL604148 | 1.00 | FPR3 (0.51) | FPR3FPR2GPR119ALOX5APFEN1 | |
| SCHEMBL4314068 | 0.94 | ALOX5AP (0.47) | FPR3FPR2GPR119ALOX5APFEN1 | |
| SCHEMBL4314074 | 0.94 | ALOX5AP (0.47) | FPR3FPR2GPR119ALOX5APFEN1 | |
| SCHEMBL2889430 | 0.90 | GPR119 (0.44) | FPR3FPR2GPR119ALOX5APFEN1 | |
| SCHEMBL2889380 | 0.89 | GPR119 (0.49) | GPR119ALOX5APFEN1CHEK2HRH2 | |
| SCHEMBL6535537 | 0.89 | GPR119 (0.49) | GPR119ALOX5APFEN1DPP4CHEK2 | |
| SCHEMBL4326309 | 0.89 | GPR119 (0.49) | GPR119ALOX5APFEN1CHEK2HRH2 | |
| SCHEMBL14045135 | 0.89 | GPR119 (0.49) | GPR119ALOX5APFEN1DPP4CHEK2 | |
| SCHEMBL6535548 | 0.89 | GPR119 (0.49) | GPR119ALOX5APFEN1DPP4KMT2A | |
| SCHEMBL4314692 | 0.89 | GPR119 (0.49) | GPR119ALOX5APFEN1CHEK2HRH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120040977-A1 | INHIBITORS OF HCV NS5A | PRESIDIO PHARMACEUTICALS, INC. (US) | 2012-02-16 | — | — | US | disclosed |
| EP-2398474-A1 | INHIBITORS OF HCV NS5A | Presidio Pharmaceuticals, Inc. (US) | 2011-12-28 | — | — | EP | disclosed |
| WO-2010096777-A1 | INHIBITORS OF HCV NS5A | PRESIDIO PHARMACEUTICALS, INC. (US) | 2010-08-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120040977-A1 | INHIBITORS OF HCV NS5A | HAVCR2, MAVS, EIF2AK2 | FPR3 3830/4885FPR2 4253/4885GPR119 3141/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.