⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1289796 | 0.80 | — | — | |
| SCHEMBL294437 | 0.77 | — | — | |
| SCHEMBL5451544 | 0.76 | — | — | |
| SCHEMBL29272681 | 0.74 | TDP1 (0.48) | — | |
| SCHEMBL10863700 | 0.74 | KMT2A (0.56) | — | |
| SCHEMBL14699752 | 0.72 | — | — | |
| SCHEMBL23170133 | 0.71 | TDP1 (0.58) | — | |
| SCHEMBL9172741 | 0.71 | — | — | |
| SCHEMBL1289844 | 0.71 | — | — | |
| Asparagine SCHEMBL288094 | 0.69 | ALOX15 (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0206037-B1 | CARBAMATES AND UREAS OF N-(2-AMINOACYLAMIDO-2-DESOXY-HEXOSYL) AMIDE, METHOD FOR THEIR PREPARATION AND THEIR PHARMACEUTICAL USE | BAYER AG (DE) | 1992-01-15 | — | — | EP | claimed |
| EP-0206037-A2 | Carbamates and ureas of N-(2-aminoacylamido-2-desoxy-hexosyl) amide, method for their preparation and their pharmaceutical use | BAYER AG (DE) | 1986-12-30 | — | — | EP | claimed |
| US-20060089355-A1 | Methods of treating alzheimer's disease using aromatically substituted w-amino-alkanoic acid amides and alkanoic acid diamides | ELAN PHARMACEUTICALS, INC. | 2006-04-27 | — | — | US | disclosed |
| WO-2003103652-A1 | METHODS OF TREATING ALZHEIMER’S DISEASE USING AROMATICALLY SUBSTITUTED ω-AMINO-ALKANOIC ACID AMIDES AND ALKANOIC ACID DIAMIDES | ELAN PHARMACEUTICALS, INC. (US) | 2003-12-18 | — | — | WO | disclosed |
| US-5641778-A | EXHIBIT RENIN-INHIBITING PROPERTIES AND CAN BE USED AS ANTIHYPERTENSIVE AGENTS | CIBA-GEIGY CORPORATION (US) | 1997-06-24 | — | — | US | disclosed |
| EP-0716077-A1 | Aromatically substituted omega amino alcanoic acid amides and alcanoic diamides and their use as renine inhibitors | CIBA-GEIGY AG (CH) | 1996-06-12 | — | — | EP | disclosed |