SCHEMBL6044858

SCHEMBL6044858

NCCCCCSCCCCCN

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 8/20 0.57
CA12 O43570 2/20 0.57
CA1 P00915 2/20 0.57
CA2 P00918 2/20 0.57
CA3 P07451 2/20 0.57
CA4 P22748 2/20 0.57
CA6 P23280 2/20 0.57
CA5A P35218 2/20 0.57
CA7 P43166 2/20 0.57
CA9 Q16790 2/20 0.57
CA14 Q9ULX7 2/20 0.57
CA5B Q9Y2D0 2/20 0.57
TSHR P16473 2/20 0.57
LMNA P02545 1/20 0.57
BLM P54132 1/20 0.57
NFKB1 P19838 1/20 0.50
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
ALDH1A1 P00352 1/20 0.42
EPHX1 P07099 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4203261 1.00 DNM1 (0.57) DNM1CA12CA1CA2CA3
SCHEMBL28158958 0.94 DNM1 (0.50) DNM1CA12CA1CA2CA3
SCHEMBL8589315 0.86 DNM1 (0.68) DNM1CA12CA1CA2CA3
SCHEMBL21318434 0.86 DNM1 (0.68) DNM1CA12CA1CA2CA3
SCHEMBL11180355 0.86 DNM1 (0.60) DNM1CA12CA1CA2CA3
SCHEMBL422834 0.85
Hydrochloric Acid SCHEMBL10953926 0.84 TDP1 (0.50) DNM1CA12CA1CA2CA3
Bromide SCHEMBL7747955 0.84 DNM1 (0.70) DNM1CA12CA1CA2CA3
SCHEMBL23471184 0.82
SCHEMBL8033562 0.82 DNM1 (0.44) DNM1CA12CA1CA2CA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11242471-B2 Conductive composition and conductive molded article MITSUBOSHI BELTING LTD. (JP) 2022-02-08 US disclosed
EP-3112425-A1 CONDUCTIVE COMPOSITION AND CONDUCTIVE MOLDED ARTICLE Mitsuboshi Belting Ltd. (JP) 2017-01-04 EP disclosed
US-20160362585-A1 Conductive Composition and Conductive Molded Article MITSUBOSHI BELTING LTD. (JP) 2016-12-15 US disclosed
EP-2559720-A1 CROSSLINKED COMPOSITION Daicel Corporation (JP) 2013-02-20 EP disclosed
US-20130026458-A1 CROSSLINKABLE COMPOSITION DAICEL CORPORATION (JP) 2013-01-31 US disclosed
CN-1266118-C Novel delta-amino-gamma-hydroxy-omega-aryl-alkanoic acid amides NOVARTIS AG (CH) 2006-07-26 CN disclosed
US-20060154926-A1 Methods of treating alzheimer's disease using aryl alkanoic acid amides ELAN PHARMACEUTICALS, INC. 2006-07-13 US disclosed
CN-1550491-A Novel delta-amino-gamma-hydroxy-omega-aryl-alkanoic acid amides ��˹��ŵ�� 2004-12-01 CN disclosed
CN-1153759-C Novel delta-amino-gamma hydroxy-omega-aryl-alkanamides ��˹��ŵ�� 2004-06-16 CN disclosed
WO-2003103653-A1 METHODS OF TREATING ALZHEIMER'S DISEASE USING ARYL ALKANOIC ACID AMIDES ELAN PHARMACEUTICALS, INC. (US) 2003-12-18 WO disclosed
US-5705658-A HYPOTENSIVE AGENTS NOVARTIS CORPORATION (US) 1998-01-06 US disclosed
US-5654445-A INTERMEDIATES FOR RENIN INHIBITORS, HYPOTENSIVE AGENTS CIBA-GEIGY CORPORATION (US) 1997-08-05 US disclosed
US-5646143-A FOR TREATING A VARIETY OF CONDITIONS CIBA-GEIGY CORPORATION (US) 1997-07-08 US disclosed
US-5627182-A RENIN INHIBITORS FOR USE AS HYPOTENSIVE AGENTS CIBA GEIGY CORPORATION (US) 1997-05-06 US disclosed
US-5559111-A HYPOTENSIVE AGENTS; RENIN INHIBITORS; Aliskiren CIBA-GEIGY CORPORATION (US) 1996-09-24 US disclosed
CN-1117960-A Novel delta-amino-gamma hydroxy-omega-aryl-alkanamides CIBA GEIGY AG (CH) 1996-03-06 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130026458-A1 CROSSLINKABLE COMPOSITION DDC, ODC1, SRM DNM1 3876/4885CA12 3427/4885CA1 1891/4885
US-20060154926-A1 Methods of treating alzheimer's disease using aryl alkanoic acid amides BACE1, APP, PSEN1 DNM1 1347/4885CA12 2443/4885CA1 221/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.