Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.48 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.48 |
| ▸ | FABP1 | P07148 | 1/20 | 0.47 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 3/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 2/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1306542 | 0.76 | CA1 (0.64) | MEN1KMT2ARAB9APOLBENPP2 | |
| SCHEMBL1250713 | 0.75 | KMT2A (0.60) | MEN1KMT2ARAB9APOLBNPSR1 | |
| SCHEMBL7231980 | 0.75 | P2RY14 (0.75) | MEN1KMT2ARAB9APOLBPKM | |
| SCHEMBL3502682 | 0.74 | ALDH1A1 (0.75) | MEN1KMT2ARAB9APOLBNPC1 | |
| SCHEMBL1250706 | 0.74 | ANPEP (0.66) | MEN1KMT2APOLBNPSR1CA12 | |
| SCHEMBL15248673 | 0.72 | NPSR1 (0.49) | MEN1KMT2APOLBNPSR1L3MBTL1 | |
| SCHEMBL24236725 | 0.72 | MEN1 (0.61) | MEN1KMT2ARAB9APOLBNPSR1 | |
| SCHEMBL16270607 | 0.72 | P2RY14 (0.75) | MEN1KMT2ARAB9APOLBPKM | |
| SCHEMBL19189821 | 0.71 | L3MBTL1 (0.81) | MEN1KMT2ARAB9APOLBPKM | |
| SCHEMBL15094713 | 0.71 | L3MBTL1 (0.64) | MEN1KMT2ARAB9APOLBPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060004085-A1 | Inhibitors of the S100-p53 protein-protein interaction and method of inhibiting cancer employing the same | UNIVERSITY OF MARYLAND , BALTIMORE | 2006-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060004085-A1 | Inhibitors of the S100-p53 protein-protein interaction and method of inhibiting cancer employing the same | TP53, S100P, S100A4 | MEN1 3359/4885KMT2A 4280/4885RAB9A 3367/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.