Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | ALPI | P09923 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | XIAP | P98170 | 1/20 | 0.46 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CPA1 | P15085 | 2/20 | 0.43 |
| ▸ | CPA3 | P15088 | 2/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
| ▸ | CPB1 | P15086 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL547221 | 1.00 | LMNA (0.49) | LMNAALDH1A1POLBHSD17B10L3MBTL1 | |
| SCHEMBL547202 | 1.00 | LMNA (0.49) | LMNAALDH1A1POLBHSD17B10L3MBTL1 | |
| SCHEMBL7270975 | 0.85 | ALDH1A1 (0.49) | LMNAALDH1A1POLBHSD17B10L3MBTL1 | |
| SCHEMBL7454025 | 0.84 | LMNA (0.41) | LMNAALDH1A1POLBHSD17B10L3MBTL1 | |
| SCHEMBL6950934 | 0.84 | LMNA (0.41) | LMNAALDH1A1POLBHSD17B10L3MBTL1 | |
| SCHEMBL6950145 | 0.84 | LMNA (0.41) | LMNAALDH1A1POLBHSD17B10L3MBTL1 | |
| SCHEMBL7452372 | 0.84 | LMNA (0.41) | LMNAALDH1A1POLBHSD17B10L3MBTL1 | |
| SCHEMBL7298422 | 0.84 | CPA1 (0.45) | LMNAALDH1A1POLBHSD17B10L3MBTL1 | |
| SCHEMBL623615 | 0.83 | CYP1A2 (0.42) | ALDH1A1POLBHSD17B10L3MBTL1CYP1A2 | |
| SCHEMBL1063981 | 0.82 | CYP1A2 (0.52) | LMNAALDH1A1POLBHSD17B10L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060105375-A1 | Bioretrosynthetic methods for preparing products and compositions related thereto | VANDERBILT UNIVERSITY | 2006-05-18 | — | — | US | disclosed |