SCHEMBL623615

SCHEMBL623615

C=CC(=O)N(CC)[C@@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.42
ALPI P09923 1/20 0.40
PKM P14618 1/20 0.40
PTGS1 P23219 1/20 0.40
XIAP P98170 1/20 0.40
SLC7A5 Q01650 1/20 0.40
MAPT P10636 2/20 0.40
ADAMTS5 Q9UNA0 1/20 0.40
ALDH1A1 P00352 1/20 0.40
CPA1 P15085 2/20 0.38
CPA3 P15088 2/20 0.38
FOLH1 Q04609 1/20 0.38
CPB1 P15086 1/20 0.38
CPB2 Q96IY4 1/20 0.38
KDM4E B2RXH2 1/20 0.38
MEN1 O00255 1/20 0.38
POLB P06746 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
PTPN7 P35236 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL547202 0.83 LMNA (0.49) CYP1A2ALPIPKMPTGS1XIAP
SCHEMBL6045641 0.83 LMNA (0.49) CYP1A2ALPIPKMPTGS1XIAP
SCHEMBL547221 0.83 LMNA (0.49) CYP1A2ALPIPKMPTGS1XIAP
SCHEMBL21351661 0.79 ALPI (0.46) CYP1A2ALPIPKMPTGS1XIAP
SCHEMBL7298422 0.78 CPA1 (0.45) CYP1A2ALPIPKMPTGS1XIAP
SCHEMBL1063983 0.76 CYP1A2 (0.52) CYP1A2ALPIPKMPTGS1XIAP
SCHEMBL1063981 0.76 CYP1A2 (0.52) CYP1A2ALPIPKMPTGS1XIAP
SCHEMBL28833017 0.76 CYP1A2 (0.44) CYP1A2ALPIPKMPTGS1XIAP
SCHEMBL7270975 0.75 ALDH1A1 (0.49) CYP1A2MAPTALDH1A1POLBKMT2A
Acrylic Acid SCHEMBL27896741 0.75 CYP1A2 (0.47) CYP1A2ALPIPKMPTGS1XIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6398962-B1 DISSOLVING A WATER-SOLUBLE POLYMER OR PORE FORMING AGENT AND A MATRIX AGENT IN A MEDIUM THAT PROMOTES THE HYDROLYSIS OF METALORGANIC COMPOUNDS TO FORM SILICON OXIDE SHAPED BODIES; SOLIDIFICATION AND ROASTING; FLUID FLOW MERCK KGAA (DE) 2002-06-04 US claimed
EP-2568994-A2 PROTEASE CATALYZED IN SITU END CAPPING OF OLIGOPEPTIDES IN AQUEOUS MEDIA Polytechnic Institute of New York University (US) 2013-03-20 EP disclosed
WO-2011143383-A9 PROTEASE CATALYZED IN SITU END CAPPING OF OLIGOPEPTIDES IN AQUEOUS MEDIA POLYTECHNIC INSTITUTE OF NEW YORK UNIVERSITY (US) 2012-02-16 WO disclosed
US-20110287479-A1 PROTEASE CATALYZED IN SITU END CAPPING OF OLIGOPEPTIDES IN AQUEOUS MEDIA POLYTECHNIC INSTITUTE OF NEW YORK UNIVERSITY (US) 2011-11-24 US disclosed
WO-2011143383-A2 PROTEASE CATALYZED IN SITU END CAPPING OF OLIGOPEPTIDES IN AQUEOUS MEDIA POLYTECHNIC INSTITUTE OF NEW YORK UNIVERSITY (US) 2011-11-17 WO disclosed
US-6398962-B1 DISSOLVING A WATER-SOLUBLE POLYMER OR PORE FORMING AGENT AND A MATRIX AGENT IN A MEDIUM THAT PROMOTES THE HYDROLYSIS OF METALORGANIC COMPOUNDS TO FORM SILICON OXIDE SHAPED BODIES; SOLIDIFICATION AND ROASTING; FLUID FLOW MERCK KGAA (DE) 2002-06-04 US disclosed