Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPFFR1 | Q9GZQ6 | 3/20 | 0.46 |
| ▸ | NPFFR2 | Q9Y5X5 | 3/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9373846 | 0.81 | NPFFR1 (0.46) | NPFFR1NPFFR2SIGMAR1MEN1ALDH1A1 | |
| SCHEMBL30122291 | 0.77 | OPRL1 (0.58) | NPFFR1NPFFR2SIGMAR1MEN1ALDH1A1 | |
| SCHEMBL6045663 | 0.72 | LMNA (0.47) | NPFFR1NPFFR2SIGMAR1MEN1ALDH1A1 | |
| SCHEMBL6045466 | 0.72 | NPFFR1 (0.46) | NPFFR1NPFFR2SIGMAR1MEN1ALDH1A1 | |
| SCHEMBL6045515 | 0.71 | NPFFR1 (0.46) | NPFFR1NPFFR2SIGMAR1MEN1ALDH1A1 | |
| SCHEMBL6123395 | 0.70 | OPRL1 (0.59) | NPFFR1NPFFR2SIGMAR1MEN1ALDH1A1 | |
| SCHEMBL9744423 | 0.70 | NPFFR1 (0.56) | NPFFR1NPFFR2SIGMAR1MEN1ALDH1A1 | |
| SCHEMBL6045533 | 0.70 | CYP3A4 (0.45) | NPFFR1NPFFR2SIGMAR1MEN1ALDH1A1 | |
| SCHEMBL6045459 | 0.70 | NPFFR1 (0.45) | NPFFR1NPFFR2SIGMAR1MEN1ALDH1A1 | |
| SCHEMBL9372890 | 0.70 | NPFFR1 (0.45) | NPFFR1NPFFR2SIGMAR1MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1035285-A | 4-five rings-4[N-(phenyl) amido of mixing] piperidine derivative and pharmaceutical composition and the method for using this compound | BOC LTD (US) | 1989-09-06 | — | — | CN | disclosed |