Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPFFR1 | Q9GZQ6 | 2/20 | 0.45 |
| ▸ | NPFFR2 | Q9Y5X5 | 2/20 | 0.45 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MC4R | P32245 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9372890 | 0.81 | NPFFR1 (0.45) | NPFFR1NPFFR2CYP3A4HSD17B10MC4R | |
| SCHEMBL30122291 | 0.76 | OPRL1 (0.58) | NPFFR1NPFFR2CYP3A4HSD17B10SIGMAR1 | |
| SCHEMBL6045724 | 0.75 | NPFFR1 (0.44) | NPFFR1NPFFR2CYP3A4HSD17B10SIGMAR1 | |
| SCHEMBL9744423 | 0.75 | NPFFR1 (0.56) | NPFFR1NPFFR2CYP3A4HSD17B10MC4R | |
| SCHEMBL6045663 | 0.74 | LMNA (0.47) | NPFFR1NPFFR2CYP3A4HSD17B10SIGMAR1 | |
| SCHEMBL6045466 | 0.73 | NPFFR1 (0.46) | NPFFR1NPFFR2CYP3A4HSD17B10MC4R | |
| SCHEMBL20493367 | 0.72 | OPRD1 (0.58) | HSD17B10SIGMAR1CYP2D6OPRD1OPRK1 | |
| SCHEMBL6045533 | 0.71 | CYP3A4 (0.45) | NPFFR1NPFFR2CYP3A4HSD17B10SIGMAR1 | |
| SCHEMBL6045437 | 0.71 | CYP2D6 (0.47) | EGLN1CYP3A4SIGMAR1CYP2C19CYP2D6 | |
| SCHEMBL6045546 | 0.71 | NPFFR1 (0.55) | NPFFR1NPFFR2CYP3A4HSD17B10SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060252797-A1 | Receptor regulator | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2006-11-09 | — | — | US | disclosed |
| EP-1559428-A1 | RECEPTOR REGULATOR | Takeda Pharmaceutical Company Limited (JP) | 2005-08-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060252797-A1 | Receptor regulator | NMUR1, NMUR2, NMBR | NPFFR1 39/4885NPFFR2 80/4885EGLN1 1986/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.