Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.41 |
| ▸ | CTSC | P53634 | 4/20 | 0.39 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.36 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.36 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.36 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.36 |
| ▸ | ARG1 | P05089 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | BLM | P54132 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL40623 | 0.84 | CYP1A2 (0.53) | CYP1A2ALOX15CYP2D6CYP2C19SLC1A3 | |
| SCHEMBL40622 | 0.84 | CYP1A2 (0.53) | CYP1A2ALOX15CYP2D6CYP2C19SLC1A3 | |
| SCHEMBL3145095 | 0.84 | CYP1A2 (0.53) | CYP1A2ALOX15CYP2D6CYP2C19SLC1A3 | |
| Hydrochloric Acid SCHEMBL1269592 | 0.82 | CYP1A2 (0.52) | CYP1A2ALOX15CYP2D6CYP2C19SLC1A3 | |
| Hydrochloric Acid SCHEMBL1269590 | 0.82 | CYP1A2 (0.52) | CYP1A2ALOX15CYP2D6CYP2C19SLC1A3 | |
| SCHEMBL661917 | 0.82 | — | — | |
| SCHEMBL187963 | 0.82 | — | — | |
| SCHEMBL901476 | 0.82 | — | — | |
| SCHEMBL900297 | 0.82 | — | — | |
| SCHEMBL16635328 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060293228-A1 | Therapeutic compositions and methods using transforming growth factor-beta mimics | BHATNAGAR RAJENDRA S | 2006-12-28 | — | — | US | disclosed |