Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 4/20 | 0.47 |
| ▸ | APEX1 | P27695 | 3/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | DNM1 | Q05193 | 6/20 | 0.43 |
| ▸ | BBOX1 | O75936 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.36 |
| ▸ | APAF1 | O14727 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12173197 | 0.97 | MEN1 (0.50) | APEX1NPSR1MEN1KMT2AACHE | |
| SCHEMBL12173199 | 0.75 | MEN1 (0.53) | APEX1NPSR1MEN1KMT2AACHE | |
| Hydrochloric Acid SCHEMBL5399827 | 0.74 | APEX1 (0.50) | APEX1NPSR1MEN1KMT2AACHE | |
| Hydrochloric Acid SCHEMBL6544618 | 0.74 | APEX1 (0.50) | APEX1NPSR1MEN1KMT2AACHE | |
| Hydrochloric Acid SCHEMBL10536364 | 0.74 | APEX1 (0.43) | APEX1NPSR1MEN1KMT2AACHE | |
| Hydrochloric Acid SCHEMBL4541161 | 0.73 | APEX1 (0.77) | APEX1NPSR1MEN1KMT2AACHE | |
| Hydrochloric Acid SCHEMBL7205565 | 0.72 | APEX1 (0.48) | APEX1NPSR1MEN1KMT2AACHE | |
| Hydrochloric Acid SCHEMBL28615936 | 0.71 | HTT (0.65) | KMT2ALMNADNM1HSP90AA1RAD52 | |
| Hydrochloric Acid SCHEMBL28622537 | 0.71 | HTT (0.65) | KMT2ALMNADNM1HSP90AA1RAD52 | |
| Hydrochloric Acid SCHEMBL28614604 | 0.71 | HTT (0.65) | KMT2ALMNADNM1HSP90AA1RAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022188513-A1 | ANTIMICROBIAL POLYLACTIC ACID MATERIAL AND PREPARATION METHOD THEREFOR | 深圳安吉尔饮水产业集团有限公司 | 2022-09-15 | — | — | WO | claimed |
| WO-2005040094-A1 | NOVEL DENDRIMER COMPOUND AND A BIOCHIP USING THE SAME | POSTECH FOUNDATION (KR) | 2005-05-06 | — | — | WO | claimed |
| CN-115990520-A | Composite carrier for supported catalyst, palladium/composite carrier catalyst, and preparation method and application thereof | 中国石油化工股份有限公司 | 2023-04-21 | — | — | CN | disclosed |
| WO-2022188513-A1 | ANTIMICROBIAL POLYLACTIC ACID MATERIAL AND PREPARATION METHOD THEREFOR | 深圳安吉尔饮水产业集团有限公司 | 2022-09-15 | — | — | WO | disclosed |
| CN-112237898-B | Strong anion type solid phase extraction column filler and preparation method thereof | 上海安谱实验科技股份有限公司 | 2022-08-30 | — | — | CN | disclosed |
| CN-110052083-B | Antibacterial glass fiber filtering membrane and preparation method thereof | 西南交通大学 | 2021-12-03 | — | — | CN | disclosed |
| CN-113106750-A | Antibacterial polylactic acid material and preparation method thereof | 深圳安吉尔饮水产业集团有限公司 | 2021-07-13 | — | — | CN | disclosed |
| US-20170369928-A1 | METHOD FOR EVALUATING DNA DAMAGE FROM ANALYTE | Sogang University Research Foundation | 2017-12-28 | — | — | US | disclosed |
| US-20060275806-A1 | Whole genome methylation profiles via single molecule analysis | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2006-12-07 | — | — | US | disclosed |
| WO-2005040094-A1 | NOVEL DENDRIMER COMPOUND AND A BIOCHIP USING THE SAME | POSTECH FOUNDATION (KR) | 2005-05-06 | — | — | WO | disclosed |
| US-5204201-A | Polymeric systems for overcoating organic photoreceptors used in liquid development xerographic applications | XEROX CORPORATION (US) | 1993-04-20 | — | — | US | disclosed |