SCHEMBL6046838

SCHEMBL6046838

O=C(O)c1cccc2c(C(=O)O)c(C#Cc3ccccc3-c3ccccc3)ccc12

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HNF4A P41235 1/20 0.45
NR4A1 P22736 1/20 0.41
NR4A2 P43354 1/20 0.41
NR4A3 Q92570 1/20 0.41
FFAR1 O14842 1/20 0.41
FABP3 P05413 1/20 0.39
FABP4 P15090 1/20 0.39
FABP5 Q01469 1/20 0.39
PRNP P04156 1/20 0.38
MAPT P10636 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
MEN1 O00255 1/20 0.38
HTT P42858 1/20 0.38
KMT2A Q03164 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
CDC25B P30305 2/20 0.38
CHRNB2 P17787 2/20 0.37
CHRNA4 P43681 2/20 0.37
CHRNB4 P30926 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5667978 0.84 CDC25B (0.42) HNF4ANR4A1NR4A2NR4A3FFAR1
SCHEMBL2747286 0.83 NPC1 (0.47) HNF4ANR4A1NR4A2NR4A3FFAR1
SCHEMBL5666602 0.82 HNF4A (0.40) HNF4ANR4A1NR4A2NR4A3PRNP
SCHEMBL5667414 0.78 HNF4A (0.54) HNF4ANR4A1NR4A2NR4A3FFAR1
SCHEMBL8890007 0.77 HNF4A (0.66) HNF4ANR4A1NR4A2NR4A3FABP3
SCHEMBL2745521 0.75 NR4A1 (0.46) NR4A1NR4A2NR4A3FABP3FABP5
SCHEMBL5668861 0.75 NR4A1 (0.40) HNF4ANR4A1NR4A2NR4A3PRNP
SCHEMBL5668325 0.74 NR4A1 (0.42) NR4A1NR4A2NR4A3PRNPMAPT
SCHEMBL28226287 0.72 ALDH1A1 (0.48) NR4A1NR4A2NR4A3MAPTKMT2A
SCHEMBL2746782 0.71 KDM4E (0.42) NR4A1NR4A2NR4A3FFAR1PRNP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7049371-B2 Material for an insulating film, coating varnish for an insulating film, and insulating film and semiconductor device using the same SUMITOMO BAKELITE COMPANY, LTD. (JP) 2006-05-23 US disclosed
US-20040002572-A1 Material for an insulating film, coating varnish for an insulating film, and insulating film and semiconductor device using the same SUMITOMO BAKELITE COMPANY, LTD. (JP) 2004-01-01 US disclosed
EP-1333050-A1 MATERIAL FOR INSULATING FILM, COATING VARNISH FOR INSULATING FILM, AND INSULATING FILM AND SEMICONDUCTOR DEVICE USING THE SAME SUMITOMO BAKELITE CO., LTD. (JP) 2003-08-06 EP disclosed