SCHEMBL5666602

SCHEMBL5666602

O=C(O)c1cccc2c(C(=O)O)c(C#Cc3cccc(-c4ccccc4)c3)ccc12

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HNF4A P41235 3/20 0.40
NR4A1 P22736 1/20 0.40
NR4A2 P43354 1/20 0.40
NR4A3 Q92570 1/20 0.40
XDH P47989 1/20 0.39
SLC22A12 Q96S37 1/20 0.39
ACMSD Q8TDX5 3/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
CDC25B P30305 2/20 0.37
DHFR P00374 1/20 0.37
MCL1 Q07820 1/20 0.37
ATM Q13315 1/20 0.37
PLAUR Q03405 1/20 0.37
PRNP P04156 1/20 0.37
PTPN1 P18031 4/20 0.36
PTPRC P08575 3/20 0.36
PTPN2 P17706 3/20 0.36
PTPN6 P29350 3/20 0.36
PTPN9 P43378 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5667978 0.90 CDC25B (0.42) HNF4ANR4A1NR4A2NR4A3ACMSD
SCHEMBL2747286 0.89 NPC1 (0.47) HNF4ANR4A1NR4A2NR4A3NPC1
SCHEMBL5667085 0.85 NPC1 (0.46) HNF4AXDHSLC22A12ACMSDNPC1
SCHEMBL6046838 0.82 HNF4A (0.45) HNF4ANR4A1NR4A2NR4A3ACMSD
SCHEMBL5666527 0.80 KMO (0.43) NPC1RAB9APTPN1GRIN2DGRIN2A
SCHEMBL5668861 0.79 NR4A1 (0.40) HNF4ANR4A1NR4A2NR4A3XDH
SCHEMBL5669133 0.76 HNF4A (0.50) HNF4AXDHSLC22A12ACMSDDHFR
SCHEMBL5668325 0.75 NR4A1 (0.42) NR4A1NR4A2NR4A3ACMSDCDC25B
SCHEMBL5669811 0.74 NPC1 (0.49) HNF4AACMSDNPC1RAB9ACDC25B
SCHEMBL2745521 0.73 NR4A1 (0.46) NR4A1NR4A2NR4A3RAB9ACDC25B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1333050-B1 MATERIAL FOR INSULATING FILM, COATING VARNISH FOR INSULATING FILM, AND INSULATING FILM AND SEMICONDUCTOR DEVICE USING THE SAME SUMITOMO BAKELITE CO (JP) 2006-12-27 EP disclosed
US-7049371-B2 Material for an insulating film, coating varnish for an insulating film, and insulating film and semiconductor device using the same SUMITOMO BAKELITE COMPANY, LTD. (JP) 2006-05-23 US disclosed
US-20040002572-A1 Material for an insulating film, coating varnish for an insulating film, and insulating film and semiconductor device using the same SUMITOMO BAKELITE COMPANY, LTD. (JP) 2004-01-01 US disclosed
EP-1333050-A1 MATERIAL FOR INSULATING FILM, COATING VARNISH FOR INSULATING FILM, AND INSULATING FILM AND SEMICONDUCTOR DEVICE USING THE SAME SUMITOMO BAKELITE CO., LTD. (JP) 2003-08-06 EP disclosed