Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.49 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.49 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL774829 | 0.85 | TXNRD1 (0.54) | TXNRD1TXNRD3TXNRD2ALDH1A1AOC3 | |
| SCHEMBL1898972 | 0.79 | TXNRD1 (0.49) | TXNRD1TXNRD3TXNRD2ALDH1A1LMNA | |
| SCHEMBL15049954 | 0.78 | TXNRD1 (0.48) | TXNRD1TXNRD3TXNRD2ALDH1A1MAPT | |
| SCHEMBL16724095 | 0.74 | TXNRD1 (0.52) | TXNRD1TXNRD3TXNRD2ALDH1A1LMNA | |
| SCHEMBL6054284 | 0.74 | TXNRD1 (0.55) | TXNRD1TXNRD3TXNRD2ALDH1A1LMNA | |
| SCHEMBL3328445 | 0.73 | TXNRD1 (0.66) | TXNRD1TXNRD3TXNRD2ALDH1A1AOC3 | |
| SCHEMBL6038159 | 0.72 | TXNRD1 (0.56) | TXNRD1TXNRD3TXNRD2AOC3MAPT | |
| SCHEMBL16722824 | 0.71 | TXNRD1 (0.51) | TXNRD1TXNRD3TXNRD2ALDH1A1AOC3 | |
| SCHEMBL3489697 | 0.70 | TXNRD1 (0.50) | TXNRD1TXNRD3TXNRD2ALDH1A1LMNA | |
| SCHEMBL5239589 | 0.69 | TXNRD1 (0.68) | TXNRD1TXNRD3TXNRD2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060154256-A1 | Method for covalently attaching nucleosides and/or nucleotides on surfaces and method for determining coupling yields in the synthesis of nucleotides | CHEMOGENIX GMBH (DE) | 2006-07-13 | — | — | US | disclosed |
| EP-1438322-A2 | METHOD FOR COVALENTLY ATTACHING NUCLEOSIDES AND/OR NUCLEOTIDES ON SURFACES AND METHOD FOR DETERMINING COUPLING YIELDS IN THE SYNTHESIS OF NUCLEOTIDES | Chemogenix GmbH (DE) | 2004-07-21 | — | — | EP | disclosed |
| WO-2003035664-A2 | METHOD FOR COVALENTLY ATTACHING NUCLEOSIDES AND/OR NUCLEOTIDES ON SURFACES AND METHOD FOR DETERMINING COUPLING YIELDS IN THE SYNTHESIS OF NUCLEOTIDES | CHEMOGENIX GMBH (DE) | 2003-05-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060154256-A1 | Method for covalently attaching nucleosides and/or nucleotides on surfaces and method for determining coupling yields in the synthesis of nucleotides | NUDT1, PNP, NME2 | TXNRD1 3244/4885TXNRD3 2182/4885TXNRD2 3414/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.