SCHEMBL6047160

SCHEMBL6047160

COc1ccc(C(OCC(O)COCCCCc2ccc3ccc4cccc5ccc2c3c45)(c2ccccc2)c2ccc(OC)cc2)cc1

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
MTNR1A P48039 4/20 0.35
SLC6A1 P30531 2/20 0.34
TDP1 Q9NUW8 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
SLC6A11 P48066 1/20 0.34
CASR P41180 1/20 0.33
CTSK P43235 1/20 0.33
MTNR1B P49286 3/20 0.33
NQO2 P16083 1/20 0.33
SIGMAR1 Q99720 1/20 0.32
GBA1 P04062 2/20 0.32
UGCG Q16739 2/20 0.32
GBA2 Q9HCG7 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10769223 0.92 KMT2A (0.44) MEN1KMT2ACTSKGBA1UGCG
SCHEMBL5384418 0.91 MEN1 (0.44) MEN1KMT2ACTSKGBA1UGCG
SCHEMBL2048837 0.88 CTSK (0.36) MEN1KMT2ASLC6A1SLC6A11CASR
SCHEMBL8663631 0.80 PLA2G2A (0.43) MEN1KMT2AGBA1UGCGGBA2
SCHEMBL13575129 0.78 CASR (0.47) MEN1KMT2ASLC6A1TDP1L3MBTL1
SCHEMBL9159602 0.78 CASR (0.47) MEN1KMT2ASLC6A1TDP1L3MBTL1
SCHEMBL30515121 0.78 CASR (0.47) MEN1KMT2ASLC6A1TDP1L3MBTL1
SCHEMBL16104620 0.78 CASR (0.47) MEN1KMT2ASLC6A1TDP1L3MBTL1
SCHEMBL15070694 0.78 CASR (0.47) MEN1KMT2ASLC6A1TDP1L3MBTL1
SCHEMBL9495170 0.78 CASR (0.47) MEN1KMT2ASLC6A1TDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1230015-B1 METHOD FOR PRODUCING FINISHED CHEMICAL SURFACES FEBIT BIOTECH GMBH (DE) 2006-07-26 EP disclosed