Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 1/20 | 0.43 |
| ▸ | ELOVL6 | Q9H5J4 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.38 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30998760 | 1.00 | STS (0.43) | STSELOVL6ALDH1A1STAT3KDM4E | |
| SCHEMBL16499819 | 0.88 | STS (0.42) | STSELOVL6ALDH1A1STAT3KDM4E | |
| SCHEMBL3973620 | 0.84 | HSD11B1 (0.49) | STSMEN1KMT2A | |
| SCHEMBL12794680 | 0.84 | HSD11B1 (0.49) | STSMEN1KMT2A | |
| SCHEMBL19461293 | 0.84 | STS (0.41) | STSELOVL6STAT3 | |
| SCHEMBL18396809 | 0.82 | STAT3 (0.45) | ALDH1A1STAT3KDM4ECYP2D6MEN1 | |
| SCHEMBL23501221 | 0.82 | CACNA1H (0.39) | STSELOVL6ALDH1A1STAT3KDM4E | |
| SCHEMBL15727886 | 0.80 | GAA (0.43) | ALDH1A1STAT3CYP2D6KMT2ACYP2C9 | |
| SCHEMBL23245584 | 0.80 | STAT3 (0.43) | ALDH1A1STAT3KDM4ECYP2D6MEN1 | |
| SCHEMBL17815986 | 0.80 | ALDH1A1 (0.49) | ALDH1A1STAT3MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1682142-A2 | M3 MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2006-07-26 | — | — | EP | disclosed |
| WO-2005046586-A2 | M3 MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2005-05-26 | — | — | WO | disclosed |