Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.48 |
| ▸ | GPR119 | Q8TDV5 | 13/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | STS | P08842 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12794680 | 1.00 | HSD11B1 (0.49) | HSD11B1CHRM2CHRM1CHRM3GPR119 | |
| SCHEMBL16499643 | 0.89 | HSD11B1 (0.47) | HSD11B1CHRM2CHRM1CHRM3GPR119 | |
| SCHEMBL23265405 | 0.86 | HSD11B1 (0.44) | HSD11B1CHRM2CHRM1CHRM3GPR119 | |
| SCHEMBL26143890 | 0.84 | MMP13 (0.43) | HSD11B1CHRM2CHRM1CHRM3GPR119 | |
| SCHEMBL6047460 | 0.84 | STS (0.43) | MEN1KMT2ASTS | |
| SCHEMBL30998760 | 0.84 | STS (0.43) | MEN1KMT2ASTS | |
| SCHEMBL30586531 | 0.84 | MMP13 (0.46) | HSD11B1GPR119MMP13MEN1KMT2A | |
| SCHEMBL216692 | 0.84 | GPR119 (0.58) | GPR119MMP13MEN1KMT2ASTS | |
| SCHEMBL20765293 | 0.84 | HSD11B1 (0.51) | HSD11B1CHRM2CHRM1CHRM3GPR119 | |
| SCHEMBL30661336 | 0.84 | HSD11B1 (0.51) | HSD11B1CHRM2CHRM1CHRM3GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1682142-B1 | M3 MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS | GLAXO GROUP LTD (GB) | 2012-07-11 | — | — | EP | disclosed |
| US-7906531-B2 | M3 muscarinic acetylcholine receptor antagonists | GLAXO GROUP LIMITED (GB) | 2011-03-15 | — | — | US | disclosed |
| US-20090275604-A1 | M3 Muscarinic Acetylcholine Receptor Antagonists | GLAXO GROUP LIMITED | 2009-11-05 | — | — | US | disclosed |
| US-7563803-B2 | M3 muscarinic acetylcholine receptor antagonists | GLAXO GROUP LIMITED (GB) | 2009-07-21 | — | — | US | disclosed |
| US-7439255-B2 | Muscarinic acetylcholine receptor antagonists | GLAXO GROUP LIMITED (GB) | 2008-10-21 | — | — | US | disclosed |
| US-20070270456-A1 | M3 Muscarinic Acetylcholine Receptor Antagonists | GLAXO GROUP LIMITED | 2007-11-22 | — | — | US | disclosed |
| US-20070129396-A1 | Muscarinic acetylcholine receptor antagonists | GLAXO GROUP LIMITED | 2007-06-07 | — | — | US | disclosed |
| EP-1682142-A2 | M3 MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2006-07-26 | — | — | EP | disclosed |
| WO-2005046586-A2 | M3 MUSCARINIC ACETYLCHOLINE RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2005-05-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070129396-A1 | Muscarinic acetylcholine receptor antagonists | CHRM3, CHRNG, CHRM2 | HSD11B1 3554/4885CHRM2 3/4885CHRM1 19/4885 |
| US-20090275604-A1 | M3 Muscarinic Acetylcholine Receptor Antagonists | CHRM3, CHRM2, CHRM5 | HSD11B1 4075/4885CHRM2 2/4885CHRM1 8/4885 |
| US-20070270456-A1 | M3 Muscarinic Acetylcholine Receptor Antagonists | CHRM3, CHRM2, CHRM5 | HSD11B1 4075/4885CHRM2 2/4885CHRM1 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.