Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT1 | Q99873 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | DRD1 | P21728 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | EYA2 | O00167 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8866410 | 1.00 | PRMT1 (0.52) | PRMT1ADRA1ATDP1KDM4ELMNA | |
| SCHEMBL8322477 | 1.00 | PRMT1 (0.52) | PRMT1ADRA1ATDP1KDM4ELMNA | |
| SCHEMBL8721538 | 1.00 | PRMT1 (0.52) | PRMT1ADRA1ATDP1KDM4ELMNA | |
| SCHEMBL14639782 | 0.88 | TDP1 (0.44) | ADRA1ATDP1KDM4ELMNACHRM2 | |
| SCHEMBL28333087 | 0.87 | PRMT1 (0.52) | PRMT1ADRA1ALMNATSHRPMP22 | |
| SCHEMBL1419475 | 0.85 | CASP2 (0.51) | ADRA1ATDP1KDM4ELMNACHRM2 | |
| SCHEMBL1419840 | 0.85 | CASP2 (0.51) | ADRA1ATDP1KDM4ELMNACHRM2 | |
| SCHEMBL1419654 | 0.85 | CASP2 (0.51) | ADRA1ATDP1KDM4ELMNACHRM2 | |
| SCHEMBL2027019 | 0.85 | CASP2 (0.51) | ADRA1ATDP1KDM4ELMNACHRM2 | |
| SCHEMBL1420133 | 0.85 | CASP2 (0.51) | ADRA1ATDP1KDM4ELMNACHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030202943-A1 | DTPA monoamides, pharmaceutical agents containing these compounds, their use and process for their production | SCHERING AKTIENGESELLSCHAFT (DE) | 2003-10-30 | — | — | US | claimed |
| US-6565830-B1 | Contrast agent for imaging | SCHERING AKTIENGESELLSCHAFT (DE) | 2003-05-20 | — | — | US | claimed |
| US-6287538-B1 | CONTRAST AGENT | SCHERING AKTIENGESELLSCHAFT (DE) | 2001-09-11 | — | — | US | claimed |
| US-5859214-A | DTPA monoamides, pharmaceutical agents containing these compounds, their use and process for their production | SCHERING AKTIENGESELLSHAFT (DE) | 1999-01-12 | — | — | US | claimed |
| US-5843399-A | DTPA monoamides for MRI | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-12-01 | — | — | US | claimed |
| US-7074387-B2 | DTPA monoamides, pharmaceutical agents containing these compounds, their use and process for their production | SCHERING AG (DE) | 2006-07-11 | — | — | US | disclosed |
| US-20030202943-A1 | DTPA monoamides, pharmaceutical agents containing these compounds, their use and process for their production | SCHERING AKTIENGESELLSCHAFT (DE) | 2003-10-30 | — | — | US | disclosed |
| US-6565830-B1 | Contrast agent for imaging | SCHERING AKTIENGESELLSCHAFT (DE) | 2003-05-20 | — | — | US | disclosed |
| US-6287538-B1 | CONTRAST AGENT | SCHERING AKTIENGESELLSCHAFT (DE) | 2001-09-11 | — | — | US | disclosed |
| US-5859214-A | DTPA monoamides, pharmaceutical agents containing these compounds, their use and process for their production | SCHERING AKTIENGESELLSHAFT (DE) | 1999-01-12 | — | — | US | disclosed |
| US-5843399-A | DTPA monoamides for MRI | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-12-01 | — | — | US | disclosed |
| EP-0450742-B1 | DTPA-Monoamids, pharmaceutical compositions containing them, their use and process for their preparation | SCHERING AG (DE) | 1994-07-06 | — | — | EP | disclosed |
| EP-0450742-A1 | DTPA-Monoamids, pharmaceutical compositions containing them, their use and process for their preparation | SCHERING AKTIENGESELLSCHAFT (DE) | 1991-10-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030202943-A1 | DTPA monoamides, pharmaceutical agents containing these compounds, their use and process for their production | SLC43A1, HRH4, ACSL6 | PRMT1 802/4885ADRA1A 1066/4885TDP1 4794/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.