Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | G6PD | P11413 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | FBP1 | P09467 | 2/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL445246 | 0.76 | ALDH1A1 (0.41) | MAPK1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL896232 | 0.75 | LMNA (0.36) | MAPK1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL309863 | 0.73 | LMNA (0.61) | MAPK1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL8008016 | 0.73 | PTGS1 (0.59) | MAPK1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL10332372 | 0.72 | TSHR (0.41) | MEN1KMT2APTGS1PTGS2ALDH1A1 | |
| SCHEMBL18479 | 0.72 | CYP19A1 (0.52) | MAPK1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL28195381 | 0.70 | ERN1 (0.37) | MEN1KMT2AALDH1A1CYP19A1LMNA | |
| SCHEMBL6889537 | 0.70 | PKM (0.43) | MAPK1MAPTKDM4EPKMNPSR1 | |
| SCHEMBL9657631 | 0.70 | MAPT (0.56) | MAPK1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL9732800 | 0.70 | ALDH1A1 (0.50) | MAPK1MAPTMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006117556-A2 | MATERIALS AND METHODS FOR THE PHOTODIRECTED SYNTHESIS OF OLIGONUCLEOTIDE ARRAYS | THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (GB) | 2006-11-09 | — | — | WO | claimed |
| WO-2006117556-A2 | MATERIALS AND METHODS FOR THE PHOTODIRECTED SYNTHESIS OF OLIGONUCLEOTIDE ARRAYS | THE INSTITUTE OF CANCER RESEARCH: ROYAL CANCER HOSPITAL (GB) | 2006-11-09 | — | — | WO | disclosed |