Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | HTR7 | P34969 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | AQP1 | P29972 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 3/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6047921 | 0.90 | AQP1 (0.41) | BCHELMNASLC6A3ALDH1A1SMN1; SMN2 | |
| SCHEMBL4652327 | 0.87 | AQP1 (0.36) | BCHELMNAALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL6047960 | 0.85 | BCHE (0.38) | BCHEHTR1AHTR7LMNAALDH1A1 | |
| SCHEMBL6047935 | 0.85 | AQP1 (0.47) | BCHELMNACA1CA2ALDH1A1 | |
| SCHEMBL6047891 | 0.84 | PRKAB2 (0.39) | BCHEHTR7LMNAMAPK1KDM4E | |
| SCHEMBL6047953 | 0.84 | CHRM3 (0.40) | HTR1AHTR7CA1CA2SLC6A3 | |
| SCHEMBL4749762 | 0.84 | PRKAB2 (0.40) | HTR7LMNAALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL6047920 | 0.83 | BCHE (0.36) | BCHELMNAALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL6047978 | 0.83 | ALDH1A1 (0.41) | BCHELMNAALDH1A1SMN1; SMN2MAPK1 | |
| SCHEMBL6047971 | 0.83 | NPC1 (0.41) | BCHELMNAALDH1A1SMN1; SMN2NPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1675840-A1 | DIHYDROBENZOFURANYL ALKANAMINE DERIVATIVES AS 5HT2C AGONISTS | Wyeth a Corporation of the State of Delaware (US) | 2006-07-05 | — | — | EP | disclosed |
| WO-2005044812-A1 | DIHYDROBENZOFURANYL ALKANAMINE DERIVATIVES AS 5HT2C AGONISTS | WYETH A CORPORATION OF THE STATE OF DELAWARE (US) | 2005-05-19 | — | — | WO | disclosed |