SCHEMBL6047976

SCHEMBL6047976

SSC(Cl)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.50
DPP4 P27487 2/20 0.38
F2 P00734 1/20 0.38
HTR2A P28223 1/20 0.35
TAAR1 Q96RJ0 1/20 0.35
CYP2D6 P10635 2/20 0.33
SRC P12931 1/20 0.33
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2C9 P11712 1/20 0.32
SLC6A4 P31645 1/20 0.32
CYP2C19 P33261 1/20 0.32
SLC6A3 Q01959 1/20 0.32
HRH1 P35367 1/20 0.32
MTOR P42345 1/20 0.32
RAB9A P51151 1/20 0.32
GRM7 Q14831 1/20 0.32
LMNA P02545 1/20 0.32
MAPK1 P28482 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL766520 0.78 TSHR (0.55) TSHRDPP4F2HTR2ATAAR1
SCHEMBL7120944 0.78 TSHR (0.55) TSHRDPP4F2HTR2ATAAR1
SCHEMBL1575568 0.76 TSHR (0.52) TSHRDPP4F2HTR2ATAAR1
SCHEMBL775059 0.72 TSHR (0.44) TSHRDPP4F2HTR2ATAAR1
SCHEMBL11062833 0.72 TSHR (0.48) TSHRDPP4F2CYP2D6SRC
SCHEMBL5675871 0.69
SCHEMBL4127900 0.69 TSHR (0.39) TSHRSLC6A4SLC6A3
SCHEMBL2155150 0.69 TSHR (0.44) TSHRDPP4F2HTR2ATAAR1
SCHEMBL10679365 0.69 TSHR (0.44) TSHRDPP4F2HTR2ATAAR1
SCHEMBL9244313 0.68 DPP4 (0.38) TSHRDPP4F2HTR2ATAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108473902-B High pyrophosphate level lubricants 路博润公司 2022-02-01 CN disclosed
EP-3877487-A1 LUBRICANT COMPRISING A DIESTER OF ADIPIC ACID WITH A TRIDECANOL BASF SE (DE) 2021-09-15 EP disclosed
CN-107109282-B Lubricating composition with seal compatibility 路博润公司 2020-03-27 CN disclosed
EP-3390592-A1 PROTECTED MERCAPTOPHENOLS FOR LUBRICATING COMPOSITIONS The Lubrizol Corporation (US) 2018-10-24 EP disclosed
CN-106085559-B Lubricant compositions for automatic transmission 雅富顿化学公司 2017-09-19 CN disclosed
WO-2017105951-A1 PROTECTED MERCAPTOPHENOLS FOR LUBRICATING COMPOSITIONS THE LUBRIZOL CORPORATION (US) 2017-06-22 WO disclosed
CN-106661492-A Alkylphenol detergents 路博润公司 2017-05-10 CN disclosed
CN-106085559-A Lubricant compositions for automatic transmission 雅富顿化学公司 2016-11-09 CN disclosed
CN-105985845-A Lubricating oil compositions for construction machines 雪佛龙日本有限公司 2016-10-05 CN disclosed
EP-1622996-A1 SLOW RELEASE LUBRICANT ADDITIVES GEL THE LUBRIZOL CORPORATION (US) 2006-02-08 EP disclosed
US-5585338-A Aviation turbine oils of improved load carrying capacity containing mercaptobenzoic acid EXXON RESEARCH AND ENGINEERING COMPANY (US) 1996-12-17 US disclosed
US-5429758-A Oil additive, hydrogenated block polymer of styrene, butadiene and an unsaturated carboxylic monomer THE LUBRIZOL CORPORATION (US) 1995-07-04 US disclosed
EP-0285609-B1 GRAFT COPOLYMERS PREPARED FROM SOLVENT-FREE REACTIONS AND DISPERSANT DERIVATIVES THEREOF LUBRIZOL CORP (US) 1994-02-09 EP disclosed
EP-0287569-B1 OIL-SOLUBLE REACTION PRODUCTS OF AN ACYLATED REACTION PRODUCT, A POLYAMINE, AND A MONO-FUNCTIONAL ACID LUBRIZOL CORP (US) 1994-02-02 EP disclosed
EP-0287569-A1 OIL-SOLUBLE REACTION PRODUCTS OF AN ACYLATED REACTION PRODUCT, A POLYAMINE, AND A MONO-FUNCTIONAL ACID. LUBRIZOL CORP (US) 1988-10-26 EP disclosed
EP-0285609-A1 GRAFT COPOLYMERS PREPARED FROM SOLVENT-FREE REACTIONS AND DISPERSANT DERIVATIVES THEREOF. LUBRIZOL CORP (US) 1988-10-12 EP disclosed
WO-1987003897-A1 OIL-SOLUBLE REACTION PRODUCTS OF AN ACYLATED REACTION PRODUCT, A POLYAMINE, AND A MONO-FUNCTIONAL ACID THE LUBRIZOL CORPORATION (US) 1987-07-02 WO disclosed
WO-1987003890-A1 GRAFT COPOLYMERS PREPARED FROM SOLVENT-FREE REACTIONS AND DISPERSANT DERIVATIVES THEREOF THE LUBRIZOL CORPORATION (US) 1987-07-02 WO disclosed
US-4670173-A DISPERSANTS; VISCOSITY IMPROVERS; GEL-FREE THE LUBRIZOL CORPORATION (US) 1987-06-02 US disclosed
WO-1980001807-A1 MAGNESIUM OXIDE-CARBOXYLATE COMPLEXES,METHOD FOR THEIR PREPARATION,AND COMPOSITIONS CONTAINING THE SAME LUBRIZOL CORP (US) 1980-09-04 WO disclosed