Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 2/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10737879 | 0.87 | CYP2C9 (0.47) | TSHRLMNASMN1; SMN2MAPTHSD17B10 | |
| SCHEMBL11157695 | 0.85 | SLC6A3 (0.48) | TSHRLMNASMN1; SMN2MAPTCYP1A2 | |
| SCHEMBL7120944 | 0.76 | TSHR (0.55) | TSHRLMNATDP1DPP4F2 | |
| SCHEMBL766520 | 0.76 | TSHR (0.55) | TSHRLMNADPP4F2MAPK1 | |
| SCHEMBL3911663 | 0.76 | SMN1; SMN2 (0.45) | TSHRLMNASMN1; SMN2MAPTHPGD | |
| SCHEMBL9955937 | 0.74 | TDP1 (0.58) | TSHRLMNASMN1; SMN2MAPTHPGD | |
| SCHEMBL1575568 | 0.74 | TSHR (0.52) | TSHRLMNATDP1DPP4F2 | |
| SCHEMBL6076178 | 0.74 | MAPK1 (0.50) | TSHRLMNASMN1; SMN2MAPTHPGD | |
| SCHEMBL14894782 | 0.74 | SMN1; SMN2 (0.43) | TSHRLMNASMN1; SMN2MAPTHPGD | |
| SCHEMBL11364089 | 0.73 | MMP2 (0.50) | TSHRLMNAMAPTHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4478984-A | CONDENSING AN N-(CHLOROBENZYL)-PHTHALIMIDE WITH A STYRENE RESIN AND SPLITTING THE IMIDE | SMITHKLINE BECKMAN CORPORATION (US) | 1984-10-23 | — | — | US | disclosed |