Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR2 | P30874 | 1/20 | 0.44 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 9/20 | 0.39 |
| ▸ | AQP1 | P29972 | 3/20 | 0.39 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.32 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6047981 | 0.85 | AQP1 (0.37) | SSTR2SSTR4SIRT2AQP1EZH2 | |
| SCHEMBL4623673 | 0.83 | AQP1 (0.57) | SSTR2SSTR4SIRT2AQP1 | |
| SCHEMBL4596497 | 0.80 | SIRT2 (0.56) | SSTR2SSTR4SIRT2AQP1EZH2 | |
| SCHEMBL4623587 | 0.78 | PRKAB2 (0.35) | SSTR2SSTR4AQP1 | |
| SCHEMBL4225586 | 0.77 | AQP1 (0.46) | SSTR2SSTR4SIRT2AQP1EZH2 | |
| SCHEMBL4231413 | 0.75 | AQP1 (0.43) | SSTR2SSTR4SIRT2AQP1EZH2 | |
| SCHEMBL4221998 | 0.75 | AQP1 (0.52) | SSTR2SSTR4SIRT2AQP1EZH2 | |
| SCHEMBL4224424 | 0.73 | AQP1 (0.49) | SIRT2AQP1EZH2 | |
| SCHEMBL4623675 | 0.72 | AQP1 (0.57) | AQP1 | |
| SCHEMBL4225581 | 0.72 | AQP1 (0.65) | SSTR2SSTR4SIRT2AQP1EZH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1675840-A1 | DIHYDROBENZOFURANYL ALKANAMINE DERIVATIVES AS 5HT2C AGONISTS | Wyeth a Corporation of the State of Delaware (US) | 2006-07-05 | — | — | EP | disclosed |
| WO-2005044812-A1 | DIHYDROBENZOFURANYL ALKANAMINE DERIVATIVES AS 5HT2C AGONISTS | WYETH A CORPORATION OF THE STATE OF DELAWARE (US) | 2005-05-19 | — | — | WO | disclosed |