SCHEMBL6048313

SCHEMBL6048313

Oc1cc(Cl)ccc1-c1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.61
BACE1 P56817 1/20 0.58
HSD17B10 Q99714 4/20 0.56
HPGD P15428 3/20 0.56
ALDH1A1 P00352 2/20 0.56
BCL2L1 Q07817 1/20 0.56
CYP3A4 P08684 2/20 0.50
TSHR P16473 2/20 0.50
TDP1 Q9NUW8 1/20 0.50
CYP1A2 P05177 1/20 0.48
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
ALOX15 P16050 2/20 0.47
LMNA P02545 1/20 0.47
MAPT P10636 1/20 0.47
MAPK1 P28482 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
ESR2 Q92731 2/20 0.47
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28016335 0.86 HSD17B10 (0.54) ALOX5HSD17B10HPGDALDH1A1CYP3A4
SCHEMBL29383789 0.84 BACE1 (0.62) ALOX5BACE1HSD17B10HPGDALDH1A1
SCHEMBL329155 0.84 BACE1 (0.62) ALOX5BACE1HSD17B10HPGDALDH1A1
Phosphine SCHEMBL27555075 0.83 BACE1 (0.60) ALOX5BACE1HSD17B10HPGDALDH1A1
Methane SCHEMBL27581120 0.83 BACE1 (0.60) ALOX5BACE1HSD17B10HPGDALDH1A1
SCHEMBL31104724 0.82 BACE1 (0.44) ALOX5BACE1HSD17B10HPGDALDH1A1
SCHEMBL5050876 0.81 CYP1A2 (0.52) ALOX5BACE1HSD17B10HPGDALDH1A1
SCHEMBL28637714 0.81 ALOX15 (0.56) BACE1HSD17B10HPGDALDH1A1CYP3A4
SCHEMBL339112 0.80 HSD17B10 (0.65) ALOX5HSD17B10HPGDALDH1A1CYP3A4
SCHEMBL28097322 0.79 BACE1 (0.56) ALOX5BACE1HSD17B10HPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220407012-A1 ORGANIC COMPOUND, ORGANIC LIGHT-EMITTING DIODE INCLUDING ORGANIC COMPOUND, AND DISPLAY DEVICE INCLUDING ORGANIC LIGHT-EMITTING DIODE SOULBRAIN CO., LTD. (KR) 2022-12-22 US disclosed
EP-4053119-A1 ORGANIC COMPOUND, ORGANIC LIGHT-EMITTING DIODE COMPRISING SAME, AND DISPLAY DEVICE COMPRISING ORGANIC LIGHT-EMITTING DIODE Soulbrain Co., Ltd. (KR) 2022-09-07 EP disclosed
WO-2021086143-A1 ORGANIC COMPOUND, ORGANIC LIGHT-EMITTING DIODE COMPRISING SAME, AND DISPLAY DEVICE COMPRISING ORGANIC LIGHT-EMITTING DIODE 솔브레인 주식회사 2021-05-06 WO disclosed
CN-109843053-A The purposes of supersaturated water-based system is used to prepare through surface reacting calcium carbonate OMYA国际股份公司 2019-06-04 CN disclosed
US-8187473-B2 Functional transition metal silicates Raju, Kanumuru Rahul (IN) 2012-05-29 US disclosed
EP-1939175-A1 SULFONAMIDE DERIVATIVE HAVING PGD2 RECEPTOR ANTAGONISTIC ACTIVITY Shionogi&Co., Ltd. (JP) 2008-07-02 EP disclosed
US-20060281961-A1 Functional transition metal silicates KANUMURU RAHUL RAJU (IN) 2006-12-14 US disclosed
EP-1670719-A1 FUNCTIONAL TRANSITION METAL SILICATES (FTMS) RAJU, Kanumuru Rahul (IN) 2006-06-21 EP disclosed
WO-2004101435-A1 FUNCTIONAL TRANSITION METAL SILICATES (FTMS) RAJU, KANUMURU, RAHUL (IN) 2004-11-25 WO disclosed
US-4472421-A SHAMPOO BAYER AKTIENGESELLSCHAFT (DE) 1984-09-18 US disclosed
US-4360469-A Preparation of quinones by salcomine-catalyzed oxidation of phenols EASTMAN KODAK COMPANY (US) 1982-11-23 US disclosed
US-4000299-A 1-(Imidazol-1-yl)-1-[4-(4-chlorophenyl)phenoxy]-3,3-dimethylbutan-2-one, its salts and a process for their use BAYER AKTIENGESELLSCHAFT (DT) 1976-12-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220407012-A1 ORGANIC COMPOUND, ORGANIC LIGHT-EMITTING DIODE INCLUDING ORGANIC COMPOUND, AND DISPLAY DEVICE INCLUDING ORGANIC LIGHT-EMITTING DIODE OCIAD1, AOX1, OXER1 ALOX5 248/4885BACE1 305/4885HSD17B10 760/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.