SCHEMBL6048383

SCHEMBL6048383

Fc1ccc(C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)cc1

nearest known ligand 0.36

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.36
RORC P51449 1/20 0.36
KCNN4 O15554 3/20 0.35
HSD11B1 P28845 1/20 0.35
USP2 O75604 1/20 0.34
RAB9A P51151 1/20 0.34
CYP19A1 P11511 2/20 0.32
PAX8 Q06710 1/20 0.32
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA7 P43166 1/20 0.31
CA9 Q16790 1/20 0.31
ACHE P22303 1/20 0.31
CYP1A1 P04798 1/20 0.30
CYP1B1 Q16678 1/20 0.30
ESR1 P03372 1/20 0.30
ESR2 Q92731 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6556363 1.00 LMNA (0.36) LMNARORCKCNN4HSD11B1USP2
SCHEMBL6048376 0.93 KCNN4 (0.39) RORCKCNN4HSD11B1USP2RAB9A
SCHEMBL673282 0.90 LMNA (0.43) LMNACA1CA2ESR1ESR2
SCHEMBL2963352 0.83 ALDH1A1 (0.42) LMNA
SCHEMBL24870976 0.79 LMNA (0.35) LMNA
SCHEMBL24871109 0.79 LMNA (0.35) LMNA
SCHEMBL7138748 0.79 CA1 (0.41) LMNACA1CA2CA9
SCHEMBL24870926 0.79 LMNA (0.35) LMNA
SCHEMBL11217955 0.79 TSHR (0.42) LMNACYP19A1CA1CA2CA9
SCHEMBL1353222 0.79 ESR1 (0.54) LMNARAB9ACA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7081497-B2 Block copolymer and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2006-07-25 US disclosed
EP-1390333-B1 PERFLUOROALKYLPHENOL STAIN RESISTS DU PONT (US) 2004-10-13 EP disclosed
CN-1524068-A Perfluoroalkylphenol stain resists 纳幕尔杜邦公司 2004-08-25 CN disclosed
US-20040138387-A1 Block copolymer and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED 2004-07-15 US disclosed
EP-1390333-A2 PERFLUOROALKYLPHENOL STAIN RESISTS E.I. DUPONT DE NEMOURS AND COMPANY (US) 2004-02-25 EP disclosed
WO-2002055464-A2 PERFLUOROALKYLPHENOL STAIN RESISTS E.I. DUPONT DE NEMOURS AND COMPANY (US) 2002-07-18 WO disclosed
US-6326337-B1 OXIDATION AND CORROSION RESISTANCE THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE 2001-12-04 US disclosed