SCHEMBL6048396

SCHEMBL6048396

Cn1ccc(=O)n(N)c1=S

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LPO P22079 3/20 0.44
CRBN Q96SW2 1/20 0.34
BRD4 O60885 1/20 0.33
TAF1 P21675 1/20 0.33
BRPF1 P55201 1/20 0.33
CREBBP Q92793 1/20 0.33
CECR2 Q9BXF3 1/20 0.33
BRD9 Q9H8M2 1/20 0.33
KDM4E B2RXH2 2/20 0.32
KDM6A O15550 1/20 0.32
KDM4A O75164 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
KDM5C P41229 1/20 0.32
KDM2B Q8NHM5 1/20 0.32
DOHH Q9BU89 1/20 0.32
KDM2A Q9Y2K7 1/20 0.32
LMNA P02545 1/20 0.32
CYP1A2 P05177 1/20 0.32
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7267469 0.77 CRBN (0.37) CRBNBRD4TAF1BRPF1CREBBP
SCHEMBL100263 0.62 CRBN (0.44) CRBNBRD4TAF1BRPF1CREBBP
SCHEMBL1567297 0.62 CRBN (0.39) CRBN
SCHEMBL24400292 0.61 LPO (0.33) LPOCRBNBRD4BRPF1BRD9
Hydrochloric Acid SCHEMBL4988381 0.61 CRBN (0.38) CRBN
Hydrochloric Acid SCHEMBL7524493 0.61 CRBN (0.43) CRBNBRD4TAF1BRPF1CREBBP
Water SCHEMBL6505685 0.61 CRBN (0.43) CRBNBRD4TAF1BRPF1CREBBP
SCHEMBL101706 0.60 MPO (0.41) BRD4BRD9KDM4ECYP2C9LMNA
SCHEMBL7899234 0.59 CRBN (0.41) CRBNBRD4BRPF1BRD9ALDH1A1
SCHEMBL2078819 0.59 CRBN (0.37) CRBNBRD4TAF1BRPF1CREBBP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 217 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110506119-A The design of AAV capsid UNIV MASSACHUSETTS 2019-11-26 CN disclosed
CN-110456035-A Probing analysis and its application based on cell BERG LLC 2019-11-15 CN disclosed
CN-110042099-A RNA in skin and fibrotic conditions is interfered 菲奥医药公司 2019-07-23 CN disclosed
CN-106471133-B Mononucleotide detection method 贝斯4创新公司 2019-07-09 CN disclosed
CN-105378109-B Minimizing errors using uracil-DNA-N-glycosylase 雅培分子公司 2019-06-14 CN disclosed
CN-109563509-A Target the delivering nucleic acid compound certainly of the reduction size of long non-coding RNA 阿克赛医药公司 2019-04-02 CN disclosed
CN-105131067-B RNA in skin and fibrotic conditions is interfered 雷克西制药公司 2019-02-19 CN disclosed
CN-109069506-A Rad 3-related protein kinase (ATR) inhibitors of ataxia-telangiectasia mutated for use in methods of treating cancer 癌症研究协会:皇家癌症医院 2018-12-21 CN disclosed
CN-108601525-A Integrated visual morphology and cellular protein expression using resonance light scattering 明策生物医学科技私人有限公司 2018-09-28 CN disclosed
CN-104812901-B The composition and system and its application method of conferring disease resistance in plants 美国印第安纳大学研究和技术公司 2018-08-10 CN disclosed
CN-1537166-A New elongase gene and production of Delta 9-polyunsaturated fatty acids ����˹�ж���ѧ 2004-10-13 CN disclosed
CN-1531440-A Pharmaceutical composition for preventing or treating Th1 and Th2 cell-related diseases by regulating Th1/Th2 ratio - 2004-09-22 CN disclosed
CN-1526025-A Genes expressed in breast cancer as prognostic and therapeutic targets ��˹��ŵ�� 2004-09-01 CN disclosed
CN-1498271-A Potassium channel interactors protein and uses therefor ǧ��ҩƷ��˾ 2004-05-19 CN disclosed
CN-1451047-A Corynebacterium glutamicum genes encoding stress, resistance and tolerance proteins BASF AG (DE) 2003-10-22 CN disclosed
CN-1430505-A Microspheres for active embolization BIOSPHERE MEDICAL INC (US) 2003-07-16 CN disclosed
CN-1429277-A Method for detecting difference between nucleic acids FRESHGENE INC (US) 2003-07-09 CN disclosed
CN-1426307-A Protein OXFORD GLYCOSCIENCES UK LTD (GB) 2003-06-25 CN disclosed
CN-1346368-A Potassium channel interactors and uses therefor MILLENNIUM PHARM INC (US) 2002-04-24 CN disclosed
CN-1312372-A Intocostrin regulation area and nucleotide series determination and method used thereof PFIZER PRODUCTS CORP (US) 2001-09-12 CN disclosed